A. Recurrent episodes of binge eating. An episode of binge eating is characterized by both of the following: 1. Eating, in a discrete period of time (e.g., within any 2-h…
Selection criterion (High vs. low vulnerability) Drug-related behavior Drug/reinforcer Reference Novel environment reactivity(HR vs. LR) Drug-induced locomotor activity (HR > LR) Amphetamine (27) Morphine (28) Self-administration (HR > LR) Amphetamine…
Fig. 1. An anorectic anx/anx mouse and a +/+ mouse, age 17 days. 2.2 Genetics The anx mutation arose spontaneously in the second filial generation (F2) of a cross between…
Fig. 1. (a) Mean ± SEM rates of agonistic behavior for animals categorized as dominant (ranked 1 and 2) and subordinate (ranks 3 thru 5). Dominant females receive less aggressive…
Fig. 1. The stressful procedure: rats were prevented from accessing HPF, but were able to see and smell it. In this 15 min period, rats engaged in repeated movements of…
Fig. 1. Schematic timeline of the experimental procedure. See Box 1 for details. Acquisition of the conditioned stimulus CS (light)-shock association was established in a different apparatus (Fig. 3) comprised…
Fig. 1. Typical 4-h intake patterns of binge-eating resistant (BER) versus binge-eating prone (BEP) rats; N = 20/group. (a) When only chow is available the groups are indistinguishable by their…
Fig. 1. Illustrative LHSS rate-frequency curve indicating the defining parameters: asymptotic or maximum reinforcement rate (reinforcements per minute), and the M-50 and theta-0 reward thresholds in pulses per second (pps)….
Fig. 1. Mean shortening intake during the 2-h access period. Bars represent mean shortening intake for the three 2-week periods of the study. Gray bars represent rats with Daily 2-h…
Fig.1. Schematic representation of 5-HT receptor subtypes present in brain regions involved in feeding behavior. Anorexia nervosa and bulimia nervosa in humans are extremely complex compared to the “simplicity” of…
