EQUINE MEDICINE

Genetic linkage maps

Jul 9, 2017 by in EQUINE MEDICINE Comments Off on Genetic linkage maps

A third generation was also genotyped, as samples from five of the six grandparents were also available. This allowed the generation of a linkage map for ECAX as recombination in…

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Genomics of the circadian clock

Jul 9, 2017 by in EQUINE MEDICINE Comments Off on Genomics of the circadian clock

The Mammalian Clockwork Mechanism Multiple gene-protein-gene feedback loops support the mammalian molecular clock mechanism that exists in almost all mammalian cell types (Reppert & Weaver, 2002). The genes in question…

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Genomics of muscle disorders

Jul 9, 2017 by in EQUINE MEDICINE Comments Off on Genomics of muscle disorders

Eventual sequencing of the GBE1 gene coding sequences resulted in the discovery of a mutation in exon 1 that results in a premature stop codon (Ward et al., 2004). GBED was…

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The Y-Chromosome

Jul 9, 2017 by in EQUINE MEDICINE Comments Off on The Y-Chromosome

The horse Y chromosome varies considerably (more than twice as compared to the smallest known size) in length among normal individuals (Hansen, 1984; Power, 1988; our unpublished observations). This polymorphism…

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Genomics of reproduction and fertility

Jul 9, 2017 by in EQUINE MEDICINE Comments Off on Genomics of reproduction and fertility

Genetics of mare fertility After REEL and gonadal dysgenesis that are caused by chromosomal abnormalities, the most common subfertile phenotype in mares is the failure to become pregnant (Coutinho da…

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