Type I Hypersensitivity
28 Type I Hypersensitivity Chapter Outline Induction of Type I Hypersensitivity Immunoglobulin E Immunoglobulin E Production Immunoglobulin E Receptors Mast Cells Structure and Location Life History Response of Mast Cells…
PHARMACOLOGY, TOXICOLOGY & THERAPEUTICS
Organs of the Immune System
12 Organs of the Immune System Chapter Outline Sources of Lymphocytes Primary Lymphoid Organs Thymus Structure Function Thymic Hormones Bursa of Fabricius Structure Function Peyer’s Patches Structure Function Lymphoglandular Complexes…
Immunity at Body Surfaces
22 Immunity at Body Surfaces Chapter Outline The Body’s Microflora The Superorganism Controlling the Microflora Exclusion of Commensals Suppression of Inflammation Benefits of the Microflora Exclusion of Pathogens Development of…
Evolution of the Immune System
40 Evolution of the Immune System Chapter Outline Immunity in Invertebrates Physical Barriers Innate Immunity Phagocytosis Prophenoloxidase (proPO)-Activating System Antimicrobial Peptides RNA Interference Adaptive Immunity Graft Rejection Immunity in Vertebrates…
Organ-Specific Autoimmune Diseases
35 Organ-Specific Autoimmune Diseases Chapter Outline Autoimmune Endocrine Disease Lymphocytic Thyroiditis Hyperthyroidism Lymphocytic Parathyroiditis Insulin-Dependent Diabetes Mellitus Atrophic Lymphocytic Pancreatitis Autoimmune Adrenalitis Autoimmune Neurological Disease Equine Polyneuritis Canine Polyneuritis Steroid-Responsive…
Regulation of Adaptive Immunity
20 Regulation of Adaptive Immunity Chapter Outline Tolerance T Cell Tolerance Central T Cell Tolerance Negative Selection Receptor Editing Peripheral T Cell Tolerance Clonal Anergy B Cell Tolerance Peripheral B…
Helper T Cells and Their Response to Antigen
14 Helper T Cells and Their Response to Antigen Chapter Outline Immunoglobulin Superfamily T Cell Antigen Receptor Antigen-Binding Component Signal Transduction Component CD3 Complex CD4 and CD8 Co-stimulators Co-stimulatory Receptors…
T Cell Function and the Destruction of Cell-Associated Invaders
18 T Cell Function and the Destruction of Cell-Associated Invaders Chapter Outline Endogenous Antigens Apoptosis Cell Cooperation Cytotoxic T Cell Responses Perforin Pathway Adhesion Phase Lethal Hit CD95 Pathway Cytotoxic…
How Antigen-Binding Receptors Are Made
17 How Antigen-Binding Receptors Are Made Chapter Outline Receptor-Antigen Binding Antigen Receptor Genes Immunoglobulin/B Cell Receptor Diversity Gene Recombination IGL Locus IGK Locus IGH Locus Generation of Junctional Diversity Gene…
Antibodies: Soluble Antigen Receptors
16 Antibodies Soluble Antigen Receptors Chapter Outline Immunoglobulins Immunoglobulin Classes Immunoglobulin G Immunoglobulin M Immunoglobulin A Immunoglobulin E Immunoglobulin D Three-Dimensional Structure of Immunoglobulins Immunoglobulin Variants Subclasses Allotypes Idiotypes Production…
