Rodent Models of l-DOPA-Induced Dyskinesia
Fig. 1. (a) During a chronic treatment period with daily injections of l-DOPA at low doses, the rodents will gradually develop abnormal involuntary movements, reaching a plateau after 10–14 days…
Electrophysiological Analysis of Movement Disorders in Mice
Fig. 1. Preparations used for electrophysiological recordings. Schematic representation of some of the most common electrophysiological techniques. Top left: Acutely dissociated neuron with two recording electrodes and sample traces of…
Sham Feeding in Rats Translates into Modified Sham Feeding in Women with Bulimia Nervosa and Purging
A. Recurrent episodes of binge eating. An episode of binge eating is characterized by both of the following: 1. Eating, in a discrete period of time (e.g., within any 2-h…
Saccharin Preference in Rats: Relation to Impulsivity and Drug Abuse
Selection criterion (High vs. low vulnerability) Drug-related behavior Drug/reinforcer Reference Novel environment reactivity(HR vs. LR) Drug-induced locomotor activity (HR > LR) Amphetamine (27) Morphine (28) Self-administration (HR > LR) Amphetamine…
The Anorectic Phenotype of the anx/anx Mouse Is Related to Hypothalamic Dysfunction
Fig. 1. An anorectic anx/anx mouse and a +/+ mouse, age 17 days. 2.2 Genetics The anx mutation arose spontaneously in the second filial generation (F2) of a cross between…
Binge Eating in Female Rats Induced by Yo-Yo Dieting and Stress
Fig. 1. The stressful procedure: rats were prevented from accessing HPF, but were able to see and smell it. In this 15 min period, rats engaged in repeated movements of…
Psychosocial Stress and Diet History Promote Emotional Feeding in Female Rhesus Monkeys
Fig. 1. (a) Mean ± SEM rates of agonistic behavior for animals categorized as dominant (ranked 1 and 2) and subordinate (ranks 3 thru 5). Dominant females receive less aggressive…
Food Seeking in Spite of Harmful Consequences
Fig. 1. Schematic timeline of the experimental procedure. See Box 1 for details. Acquisition of the conditioned stimulus CS (light)-shock association was established in a different apparatus (Fig. 3) comprised…
Binge-Prone Versus Binge-Resistant Rats and Their Concomitant Behavioral Profiles
Fig. 1. Typical 4-h intake patterns of binge-eating resistant (BER) versus binge-eating prone (BEP) rats; N = 20/group. (a) When only chow is available the groups are indistinguishable by their…
Food Restriction and Reward in Rats
Fig. 1. Illustrative LHSS rate-frequency curve indicating the defining parameters: asymptotic or maximum reinforcement rate (reinforcements per minute), and the M-50 and theta-0 reward thresholds in pulses per second (pps)….
