Fig. 1. VM tumor cells express extensive brain invasion. The VM-M2 and VM-M3 tumors are diffusely invasive into the neural parenchyma showing multiple tumor foci in the hippocampal region of…

Fig. 1. WHO pathological grading and molecular characterization of adult GBMs. (a) Diffuse gliomas are pathologically graded by the WHO. Grade I astrocytomas, also known as pilocytic astrocytomas, are found…

Isotope source of signal Main γ energy (keV) Period (h) Labeled agent category Target category 99mTc 140 6 • Antibodies • Cells • Ligands • Nucleic acids • Peptides • Proteins • Nanoparticles compounds • Antigens • Adhesion molecules…

Fig. 1. Schematic drawing of PET image signal generation. An intravenously injected imaging or reporter probe, such as a radiolabelled PET tracer, can be an enzyme substrate, a receptor ligand,…

Fig. 1. (a) Table with information relating to the biological features of syngeneic mouse GBM models including effective therapies. (b) Diagram depicting the stereotactic coordinates for injection of syngeneic mouse…

sodium chloride   3. 1-ml Syringes and 26needles   4. Ophthalmic ointment   5. Commercial depilating cream   6. Gauzes   7. Betadine surgical scrub   8. 70% Ethanol  …

and William A. Weiss2 (1) The W.A. Weiss Lab, University of California, San Francisco, San Francisco, CA, USA (2) Departments of Neurology, Pediatrics, and Neurological Surgery, University of California, San Francisco, San…

Fig. 1. Histopathology of a representative human pilocytic astrocytoma (WHO grade I). (a) Glial fibrillary acidic protein (GFAP) immunostaining demonstrates the presence of neoplastic glial cells. (b) Hematoxylin and eosin…

(1) Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden   Abstract Oligodendroglial tumors are primary tumors of the central nervous system that largely affect adults. The cell of…

, Bryan D. Choi2 and Duane A. Mitchell3 (1) Department of Pathology, Duke University Medical Center, Durham, NC, USA (2) Duke Brain Tumor Immunotherapy Program, Division of Neurosurgery, Department of Surgery and Department of…