Fig. 1. HRMAS spectra from normal mouse brain (C57/BL6) acquired at 37°C and 9.4 T (pulse-and-acquire sequence) with 6,000 Hz spinning rate, in 17 min. (a) Mouse euthanised with focused microwave (FMW) irradiation…
and Donna L. Senger1 (1) Hughes Childhood Cancer Research Program, Department of Oncology, Southern Alberta Cancer Research Institute, University of Calgary, Calgary, AB, Canada Abstract Glioblastomas are one of the deadliest…
Fig. 1. VM tumor cells express extensive brain invasion. The VM-M2 and VM-M3 tumors are diffusely invasive into the neural parenchyma showing multiple tumor foci in the hippocampal region of…
Fig. 1. WHO pathological grading and molecular characterization of adult GBMs. (a) Diffuse gliomas are pathologically graded by the WHO. Grade I astrocytomas, also known as pilocytic astrocytomas, are found…
Isotope source of signal Main γ energy (keV) Period (h) Labeled agent category Target category 99mTc 140 6 • Antibodies • Cells • Ligands • Nucleic acids • Peptides • Proteins • Nanoparticles compounds • Antigens • Adhesion molecules…
Fig. 1. Schematic drawing of PET image signal generation. An intravenously injected imaging or reporter probe, such as a radiolabelled PET tracer, can be an enzyme substrate, a receptor ligand,…
Fig. 1. (a) Table with information relating to the biological features of syngeneic mouse GBM models including effective therapies. (b) Diagram depicting the stereotactic coordinates for injection of syngeneic mouse…
sodium chloride 3. 1-ml Syringes and 26needles 4. Ophthalmic ointment 5. Commercial depilating cream 6. Gauzes 7. Betadine surgical scrub 8. 70% Ethanol …
Fig. 1. Histopathology of a representative human pilocytic astrocytoma (WHO grade I). (a) Glial fibrillary acidic protein (GFAP) immunostaining demonstrates the presence of neoplastic glial cells. (b) Hematoxylin and eosin…
