Experimental Model of Cerebral Aneurysms in Ovariectomized Rats
Fig. 13.1 Aneurysm elicitation in female Sprague Dawley rats by (1) Ligation of the bilateral posterior renal arteries for the induction of hypertension (according to the Hashimoto model) and (2)…
Murine Heart Transplantation and Graft Arterial Disease
Fig. 6.1 Representative clips for donor (left) and recipient (right) preparation during the murine heart transplant surgery 6. Make an incision on the posterior lateral thoracic cavity on the…
Photochemically Induced Endothelial Injury
Fig. 4.1 The principle of photochemical reactions. Rose bengal, which belongs to the dye class of photosensitizers, is an efficient photosensitizer of the photodynamic type (type II), producing singlet molecular…
Mouse Model of Abdominal Aortic Aneurysm Induced by CaCl2
Fig. 10.1 Macroscopic and microscopic images of the Ca model. Macroscopic images (a) and microscopic images (b, c) using Elastica van Gieson (EVG) and hematoxylin and eosin (HE) stains. Bars…
Analysis of Kawasaki Disease Using a Mouse Model, CAWS Vasculitis in DBA/2 Mice, Induced with a Water-Soluble Extracellular Polysaccharide Fraction Obtained from Candida albicans
Fig. 15.1 Severe aortic valve stenosis of CAWS arteritis in DBA/2 mice CAWS treatment DBA/2 mice were administered with CAWS via peritoneal injections for five consecutive days (a) Untereated aortic…
A Model of Stroke and Vascular Injury in the Brain
Fig. 14.1 Preparation of the intraluminal suture. (a) The intraluminal suture for the middle cerebral artery occlusion model. (b) The tip of the 6-monofilament was rounded using a soldering iron….
Murine Models of Thrombosis and Hemostasis
Fig. 5.1 Infrarenal vena cava (IVC) stasis model, showing 48-h thrombus within the IVC (a) with ligation site at lower left, and after opening the IVC (b), with scale bar…
Mouse Models of Atherosclerosis
Mouse models Diets Reported duration for atherosclerotic lesion formation Reference no. Apoe−/− Normal chow diet 16–20 weeks old [72] Human ApoE*3 Leiden transgenic High-fat/high-cholesterol diet 16 weeks [20] Ldlr−/− High-fat/high-cholesterol diet 16–20 weeks…
Wire-Mediated Endovascular Injury that Induces Rapid Onset of Medial Cell Apoptosis Followed by Reproducible Neointimal Hyperplasia
Fig. 1.1 The endovascular injury of the murine femoral artery Either the left or right femoral artery was exposed by blunted dissection and looped proximally and distally with a 6-0…
