Chapter 9 Reproduction of the rat, mouse, dog, non-human primate and minipig Dianne Creasey Introduction The reproductive system has been assigned a separate chapter for a number of reasons. Most…
Chapter 5 Hamsters and guinea pigs Elizabeth F. McInnes Hamsters Introduction The total numbers of Syrian hamsters (Mesocricetus auratus) used in biomedical research is much less than the numbers of…
Chapter 7 New Zealand White rabbit Alys E. Bradley Introduction Rabbits are classified in the order Lagomorpha. They differ from rodents in that they possess an additional pair of incisor…
Chapter 3 Beagle dog Cheryl Scudamore Introduction The majority of dogs used in toxicity studies are young beagles (generally less than one year old at the start of study), and…
Chapter 8 Artifacts in histopathology Elizabeth F. McInnes Introduction What one may see upon microscopic examination of sections of animal tissues is not always related to the normal histology or…
Section 2 Red Blood Cells Normal Morphology (Discocytes and Normocytes) Anemia Polycythemia Morphologic Changes Associated with Disease Rouleaux Agglutination Polychromasia Reticulocytes Hypochromia Anisocytosis Macrocytosis Microcytosis Poikilocytosis Leptocytes: Target Cells (Codocytes)…
Section 3 White Blood Cells Normal Leukocyte Count Leukocytosis Leukopenia Neutrophils Mature (Segmented) Neutrophils Band Neutrophils Metamyelocytes Myelocytes Promyelocytes Myeloblasts Barr Body Hypersegmented Neutrophils Pelger-Huët and Pseudo-Pelger-Huët Neutrophils Toxic Changes…
Section 5: Hematopoietic Neoplasia Overview Lymphoid Leukemia Acute Lymphoblastic Leukemia Chronic Lymphocytic Leukemia T-Cell Large Granular Lymphocytic Leukemia Acute Myeloid Leukemia Acute Undifferentiated Leukemia Acute Myeloblastic Leukemia Acute Promyelocytic Leukemia…
Section 1 General Assessment Blood Smears Monolayer Feathered Edge Body Background Increased Basophilia Cytoplasmic Fragments Infectious Agents Stain Precipitation Fibrin Skin Contaminants Blood Smears Distinctive Features: Blood smears have three…
