Animal Models of Diabetic Retinopathy
Fig. 5.1 (a) Fundus photograph of the right eye of a patient with NPDR and central involvement clinically significant macular oedema. Marked exudation is observed around the fovealcentre. (b) Trypsin…
Animal Models of Autoimmune Uveitis
Type of model Model description T cell mediated response Advantages and disadvantages 1. EAU induced animal models of uveitis A. “Classical” EAU: immunization of wiId-type mice with an ocular antigen…
An Animal Model of Graves’ Orbitopathy
Inflammatory cell infiltrates in the orbital tissue of CD3+ T cells and macrophages Pathogenic autoantibodies to the thyrotropin receptor Chemosis characterized by histopathological signs of inflammatory, congested blood vessels, and…
Animal Models of Cataracts
Type of cataract Animal model/species Key references cited in review Congenital/Juvenile Transgenic Crystallins Mouse 11, 12, 13, 17, 18, 20, 52, 53, 55, 173 Rat 137, 138 Zebrafish 45,…
Epilogue
© Springer International Publishing Switzerland 2016Chi-Chao Chan (ed.)Animal Models of Ophthalmic DiseasesEssentials in Ophthalmology10.1007/978-3-319-19434-9_10 10. Epilogue Charles E. Egwuagu1 (1) Molecular Immunology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health (NIH), Bethesda,…
Animal Models of Glaucoma
© Springer International Publishing Switzerland 2016Chi-Chao Chan (ed.)Animal Models of Ophthalmic DiseasesEssentials in Ophthalmology10.1007/978-3-319-19434-9_3 3. Animal Models of Glaucoma Thomas V. Johnson1 and Stanislav I. Tomarev2 (1) Wilmer Eye Institute, Johns Hopkins Hospital, 600 N Wolfe…
Animal Models of Age-Related Macular Degeneration: Subretinal Inflammation
© Springer International Publishing Switzerland 2016Chi-Chao Chan (ed.)Animal Models of Ophthalmic DiseasesEssentials in Ophthalmology10.1007/978-3-319-19434-9_4 4. Animal Models of Age-Related Macular Degeneration: Subretinal Inflammation Florian Sennlaub1, 2, 3 (1) Inserm, U 968, UPMC University Paris 06,…
Animal Models of Retinitis Pigmentosa (RP)
© Springer International Publishing Switzerland 2016Chi-Chao Chan (ed.)Animal Models of Ophthalmic DiseasesEssentials in Ophthalmology10.1007/978-3-319-19434-9_7 7. Animal Models of Retinitis Pigmentosa (RP) Bo Chang1 (1) The Jackson Laboratory, 600 Main Street, 04609 Bar Harbor, ME, USA …
Animal Models of Herpes Keratitis
© Springer International Publishing Switzerland 2016Chi-Chao Chan (ed.)Animal Models of Ophthalmic DiseasesEssentials in Ophthalmology10.1007/978-3-319-19434-9_1 1. Animal Models of Herpes Keratitis Robert L. Hendricks1, 2, 3 , Hongmin Yun1, Alexander M. Rowe1 and Kate L. Carroll1, 4 (1) Department of…
Animal Models of Ocular Tumors
© Springer International Publishing Switzerland 2016Chi-Chao Chan (ed.)Animal Models of Ophthalmic DiseasesEssentials in Ophthalmology10.1007/978-3-319-19434-9_9 9. Animal Models of Ocular Tumors Martine J. Jager1 , Jinfeng Cao1, Hua Yang2, Didier Decaudin3, Helen Kalirai4, Wietske van der Ent5, Nadine E. de Waard1, Nathalie Cassoux6, Mary E. Aronow7, Rohini…
