APP-Based Transgenic Models: The Tg2576 Model
(1) Department of Experimental Psychology, University of Oxford, Oxford, UK Abstract The search for a good animal, preferably mouse, model of Alzheimer’s disease (AD) is one of the most…
(1) Department of Experimental Psychology, University of Oxford, Oxford, UK Abstract The search for a good animal, preferably mouse, model of Alzheimer’s disease (AD) is one of the most…
and Deborah Young2 (1) Department of Molecular Medicine & Pathology,Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand (2) Department of Pharmacology & Clinical Pharmacology,Faculty of Medical…
and Maria Cristina Rosi1 (1) Department of Preclinical and Clinical Pharmacology, University of Florence, Florence, Italy Abstract The neurochemical alterations underlying the cognitive and behavioral symptoms that constitute the clinical picture…
, Debby Van Dam1 and Peter Paul De Deyn1, 2 (1) Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Belgium (2) Department of Neurology, Middelheim Hospital, ZNA, Antwerp, Belgium Abstract When…
Receptor subtype n Average Ki Range Ki D1-R 41 6.88 ± 12.3 1–58 D2-R 87 3.18 ± 3.7 1–20 D3-R 45 3.19 ± 3.31 1–45 D4-R 22 4.83 ± 7.6…
and Debby Van Dam1 (1) Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Belgium (2) Department of Neurology, Middelheim Hospital, ZNA, Antwerp, Belgium Abstract Animal models serve to…
, Christopher R. Pryce2 and Erich Seifritz3 (1) Wellcome Trust Centre for Neuroimaging, University College London, 12 Queen Square, London, WC1N 3BG, UK (2) Preclinical Laboratory for Translational Research into Affective Disorders, Clinic…
and Christopher D. Kroenke1, 2 (1) Department of Behavioral Neuroscience, Advanced Imaging Research Center, Oregon Health and Science University, Portland, OR, USA (2) Oregon Health and Science University, Portland, OR 97239, USA …
Fig. 3.1. International Classification of Functioning, Disability, and Health (modified from World Health Organization 2001). Table 3.1 Classification of test and measures Test and measure Clinical Laboratory Body structure and…
(1) Department of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA Abstract The rhesus macaque represents a pragmatic animal model for elucidating mechanisms…