Eventual sequencing of the GBE1 gene coding sequences resulted in the discovery of a mutation in exon 1 that results in a premature stop codon (Ward et al., 2004). GBED was…

The horse Y chromosome varies considerably (more than twice as compared to the smallest known size) in length among normal individuals (Hansen, 1984; Power, 1988; our unpublished observations). This polymorphism…

Genetics of mare fertility After REEL and gonadal dysgenesis that are caused by chromosomal abnormalities, the most common subfertile phenotype in mares is the failure to become pregnant (Coutinho da…

Mitochondrial DNA and Athletic Performance in Thoroughbreds In 2006, Harrison and Turrion-Gomez reported a relationship between mitochondrial DNA (mtDNA) haplotypes and athletic performance in the Thoroughbred (Harrison & Turrion-Gomez, 2006)….

The horse karyotype Ever since the correct chromosome number in the horse was determined, the equine chromosomes have been presented in several ways. However, it was not before the correct…

Molecular biology has been crucial in refuting a central dogma in equine laminitis and in organ injury in human sepsis, stating that laminar/organ injury was due to decreased blood flow,…

Functional Impact of the Genome Genomic DNA contains the “informational blueprint” of an organism, which has now been elucidated in the horse by sequencing of the equine genome (Wade et al.,…

Application of different banding techniques A variety of staining/banding techniques have been applied to analyze equine chromosomes. The ultimate goal of using these banding techniques was to exploit a range…

Noticeable lesions indicative of the disease generally appear at approximately 1.5 years of age (White et al., 2004; White et al., 2007). This means that HERDA-affected horses rarely show signs at birth…

Cream (C) is inherited as an incompletely dominant gene. In the heterozygous condition cream dilutes phaeomelanin from red to yellow, which results in palominos, buckskins, and smoky seal browns. Homozygotes…