Binge-Type Eating Induced by Limited Access to Optional Foods
Fig. 1. Mean shortening intake during the 2-h access period. Bars represent mean shortening intake for the three 2-week periods of the study. Gray bars represent rats with Daily 2-h…
Anorexia and Drugs of Abuse Abnormally Suppress Appetite, the Result of a Shared Molecular Signal Foul-Up
Fig.1. Schematic representation of 5-HT receptor subtypes present in brain regions involved in feeding behavior. Anorexia nervosa and bulimia nervosa in humans are extremely complex compared to the “simplicity” of…
Functional Magnetic Resonance Imaging in Awake Rats: Studies Relevant to Addiction and the Reward Circuitry
Fig. 1. Small animal MRI scanners available from various companies. (a) shows a refurbished 200 MHz 40 cm bore Oxford NMR system with passive shielding inside a Faraday cage. The…
Food-Anticipatory Activity: Rat Models and Underlying Mechanisms
Fig. 1. Female Wistar rats were housed in running wheel cages and had ad libitum access to chow and water (filled line, N = 8) or were subjected to an…
Modeling Binge Eating in Nonhuman Primates
Fig. 1. Mean total daily number of M&M’s® earned and wasted each candy session for the five animals who wasted M&Ms® (left panel ) and the three animals who ate…
Assessment of Stress-Independent Binge-Like Eating Behavior in Mice
Fig. 1. Daily 1-h free-choice access to a palatable, energy dense diet induces binge-like eating in mice. (a) In 129SvEv mice, 1-h intake of a highly-palatable diet (labeled HP on…
Activity-Based Anorexia in the Rat
Fig. 1. Features of anorexia nervosa and activity-based anorexia. Reproduced, with permission, from (15). 2 Materials and Procedures 2.1 Materials Induction of the activity-based anorexia model requires access to a…
Stressful Experiences in Early Life and Subsequent Food Intake
Fig. 1. Experimental paradigm. Rats were subjected to 3 h of maternal separation (MS) daily during PND 1-14, or left undisturbed (NH). MS and NH rats received social isolation stress…
Predicting and Classifying Rats Prone to Overeating Fat
Fat Lard 230 Vegetable oil 50 Carbohydrate Dextrin 97 Cornstarch 98 Sucrose 130 Protein Casein 325 Vitamin Mix 30 Mineral Mix 40 Total weight (g) 1,000 Energy density (kcal/g) 5.02…
Animal Models of Binge Eating Palatable Foods: Emergence of Addiction-Like Behaviors and Brain Changes in the Rat
Fig. 1. Meal analysis of two representative rats living in operant chambers. The one maintained on daily intermittent sucrose and chow had increased intake of sugar compared with the one…
