Antineoplastic Drugs

May 28, 2017 by in GENERAL Comments Off on Antineoplastic Drugs

I. GENERAL PRINCIPLES OF CANCER CHEMOTHERAPY A. The goal of treatment with chemotherapy in veterinary medicine is to increase the length and quality of life of patients based on an…

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Drug Interactions and Adverse Drug Reactions

May 28, 2017 by in GENERAL Comments Off on Drug Interactions and Adverse Drug Reactions

I. DRUG INTERACTIONS A. Introduction 1. Drug interactions are defined as an altered pharmacological response to one drug caused by the presence of second drug. The expected response may be…

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Topical Dermatology Therapy

May 28, 2017 by in GENERAL Comments Off on Topical Dermatology Therapy

I. INTRODUCTION. Drugs applied to the surface of the skin have four possible outcomes. (1) They may remain on the surface, where they may exert their medicinal qualities. (2) They…

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Drugs Acting on the Cardiovascular System

May 28, 2017 by in GENERAL Comments Off on Drugs Acting on the Cardiovascular System

I. DRUGS USED IN HEART FAILURE THERAPY A. Introduction 1. Heart failure occurs when abnormal cardiac function causes inadequate blood delivery to the tissues or adequate delivery only with elevated…

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Behavior-Modifying Drugs

May 28, 2017 by in GENERAL Comments Off on Behavior-Modifying Drugs

I. GENERAL CONSIDERATIONS A. Biochemical imbalance in the monoaminergic (5-HT and NE) and GABAergic neurotransmitter system have been implicated in behavioral problems seen in companion animals. B. Behavioral problems most…

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Drugs Acting on the Central Nervous System

May 28, 2017 by in GENERAL Comments Off on Drugs Acting on the Central Nervous System

I. INTRODUCTION A. Function. Drugs can alter the function of the central nervous system (CNS) to provide 1. Anticonvulsant effects 2. Tranquilization (sedation) 3. Analgesia B. Neurotransmitter–receptor relationship. Neurotransmitters released…

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Ocular Pharmacology

May 28, 2017 by in GENERAL Comments Off on Ocular Pharmacology

I. GENERAL CONSIDERATIONS. Many drugs that are used for other organs or systems, for example, the nervous, cardiovascular, immune, and endocrine systems, are used orally or parenterally for ocular disease…

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Respiratory Pharmacology

May 28, 2017 by in GENERAL Comments Off on Respiratory Pharmacology

I. INTRODUCTION The primary function of the respiratory system is gas exchange between the inspired air and the pulmonary artery blood. Because of the large surface area of the alveoli…

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Nonsteroidal Anti-inflammatory Drugs

May 28, 2017 by in GENERAL Comments Off on Nonsteroidal Anti-inflammatory Drugs

I. GENERAL CONSIDERATION. The nonsteroidal anti-inflammatory drugs (NSAIDs) discussed in this chapter fall under two classes, namely, inhibitors of prostaglandin (PG) synthesis and miscellaneous (locally applied) anti-inflammatory drugs. The PG…

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