Fig. 2.1 A table-mounted slit-lamp biomicroscope offers excellent optics with multiple options for magnification and greater numbers of options for varying slit-beam width, height, and light color, and cameras may…
Fig. 3.1 Two images from the same eye of a patient with asteroid hyalosis. The highly reflective calcium deposits in the vitreous obscure retinal details (left frame). However, with fluorescein…
Fig. 5.1 The upper eyelid from a control rabbit has diffuse infiltrates of lymphocytes and plasma cells in the dermis as a spontaneous change. H&E. 5× objective Neoplasms may arise…
Fig. 6.1 Lens from a monkey with spontaneously occurring cataracts. Histologic changes in the lens include swelling of lens fibers (bladder cells), vacuolation, and proliferation of lens epithelium (upper right)….
Fig. 1.1 Gross ocular anatomy. Human and nonhuman primate eyes are similar, with the NHP eye at approximately half the scale of the human eye. Other species presented for comparison…
Fig. 4.1 (a) ERG response of the right (top) and left eye (bottom) to a dim flash from the eye of a monkey that has been previously dark-adapted. Cursors have…
Approval date Drug name NDA chemical type b Indication c Route of administration Mar 2004 Iquix (levofloxacin) 3 Treatment of bacterial corneal ulcers Topical Jun 2004 Istalol (timolol maleate) 3…
Legislation Agency Substance/product FDCA (1938) Department of Health and Human Services (FDA) Pharmaceuticals and cosmetics FIFRA (1947) EPA Pesticides FHSA (1964) and TSCA (1977) Department of Agriculture and EPA Agriculture…
Clinical Pharmacokinetics and Pharmacodynamics Basic Information Overview and Goal(s) • Pharmacokinetics is what the body does to the drug. • Pharmacodynamics is what the drug does to the body, cell,…
Herpesvirus Basic Information Definition • Equine herpesviruses (EHVs) are ubiquitous enveloped DNA viruses that have a major economic and welfare impact on the horse industry worldwide. • Nine EHVs have…
