Ethical Considerations around using Animals in Research
Replacement Alternatives are often argued not to be ‘the real thing’, but neither are live animal models. In the field of toxicity testing, the US National Academy of Sciences17 has…
Humane Methods of Killing
A Section 2C licence includes conditions requiring the holder to keep a register of people who are competent to kill protected animals. In relation to each person named it must…
Education and Training for the Personal Licence Holder
html xmlns=”http://www.w3.org/1999/xhtml”> Chapter 1 Education and Training for the Personal Licence Holder Introduction The use of animals in research in the UK and Europe is controlled by several pieces of…
Principles of Animal Use and Experimental Design
There are many methods which can be used to minimise the effect of variation, through different experimental designs (blocking, factorial design) or statistical analyses such as analysis of variance (ANOVA)…
The Regulatory Framework
Box 3.1 Summary of protected animals and regulated procedures A protected animal is defined as ‘any living vertebrate, other than man, and any living cephalopod’. Animals are protected from defined…
Animal Husbandry, Environmental Enrichment and Occupational Health and Safety
html xmlns=”http://www.w3.org/1999/xhtml”> Chapter 5 Animal Husbandry, Environmental Enrichment and Occupational Health and Safety Animal Husbandry Experimental animals are a part of the experimental system, so it is important to minimise variation…
