Veterian Key

  NRG1–EGF+/− NRG1–TM+/− NRG1–Ig+/− NRG1–CRD+/− NRG1type1-tg Neonatal injection NRG1β1 Locomotor activity Open-field test ↑ (91, 109), =(93) ↑ (69, 95–97, 110) = (99), ↑ (111) = (100) = (102) =…

  Systemic NMDAR antagonist administration Global NMDAR genetic manipulation Cell type-specific/brain region-restricted genetic manipulation of NMDAR Molecular specificity Variable (low PCP, high MK-801) High High Cellular/regional specificity No No Yes…