1. A small amount of oxygen is transported in solution in plasma, but most is in combination with hemoglobin. 2. A molecule of hemoglobin can reversibly combine with four molecules of oxygen. 3. The binding of oxygen and hemoglobin is determined by oxygen tension. 4. The oxyhemoglobin dissociation curve can be displayed with percent saturation of hemoglobin as a function of oxygen tension. 5. The affinity of hemoglobin for oxygen varies with blood temperature, pH, carbon dioxide tension, and the intracellular concentration of certain organic phosphates. 6. As hemoglobin is depleted of oxygen, its color changes from bright red to bluish red. 7. Carbon monoxide has 200 times the affinity of oxygen for hemoglobin. 8. Methemoglobinemia occurs in certain toxic states, notably nitrite poisoning. 1. Carbon dioxide is transported in the blood both in solution in plasma and in chemical combination. 1. Oxygen demands of exercise are met by increases in blood flow, in hemoglobin levels, and in oxygen extraction from blood.
Gas Transport in the Blood
Oxygen Transport
A Small Amount of Oxygen Is Transported in Solution in Plasma, but Most Is in Combination with Hemoglobin
The Affinity of Hemoglobin for Oxygen Varies with Blood Temperature, pH, Carbon Dioxide Tension, and the Intracellular Concentration of Certain Organic Phosphates
You may also need

Full access? Get Clinical Tree

