23 DISSEMINATED INTRAVASCULAR COAGULATION AND THROMBOSIS 1 What is disseminated intravascular coagulation (DIC)? Disseminated intravascular coagulation is the result of a primary inflammatory or tissue-damaging process. DIC is a complex…

20 OVERVIEW: HEMOSTATIC COMPONENTS AND DISORDERS 1 What is hemostasis? Hemostasis is the maintenance of vascular integrity and blood fluidity necessary for the normal function of blood. The term hemostasis…

22 DISORDERS OF SECONDARY HEMOSTASIS (COAGULATION DEFECTS) 1 What is secondary hemostasis, and what are associated tests? Secondary hemostasis is the sequential activation of coagulation proteins (factors) resulting in conversion…

21 PLATELETOPATHIES 1 What is the clinical presentation of thrombocytopenia in dogs and cats? The clinical impression of thrombocytopenia, thrombocytopathia, and endothelial cell problems cannot easily be differentiated based on…

16 MYELODYSPLASTIC SYNDROMES Tarja Juopperi, Heather Leigh DeHeer 1 Define the term myelodysplastic syndrome. The term myelodysplastic syndrome (MDS) refers to a heterogeneous group of hematologic disorders characterized clinically by…

15 CHRONIC MYELOPROLIFERATIVE DISORDERS Tarja Juopperi, Heather Leigh DeHeer 1 What are chronic myeloproliferative disorders? Chronic myeloproliferative disorders (CMPDs) are clonal bone marrow disorders that result in the production of…

13 MYELOPROLIFERATIVE DISORDERS Tarja Juopperi, Heather Leigh DeHeer 1 Define the term leukemia. The term leukemia literally means “white blood.” This term was initially used to describe disorders characterized by…

14 ACUTE MYELOID LEUKEMIAS Tarja Juopperi, Heather Leigh DeHeer 1 What are acute myeloid leukemias? Acute myeloid leukemias (AMLs) are disorders that result from the uninhibited proliferation of a clone…

12 DISORDERS AND LABORATORY EVALUATION Ronald D. Tyler, Rick L. Cowell, James H. Meinkoth 1 What is protein dyscrasia? Protein dyscrasia refers to a protein with an abnormal structure, as…