Table 28-4 Pharmacokinetic Data for Selected Opioids in Dogs or Cats∗227 AUC, Area under the curve; Vdss, volume of distribution at steady state; CL, clearance; MRT, mean residence time; F,…
Chapter 29 Antiinflammatory Drugs Dawn Merton Boothe Chapter Outline THE PATHOPHYSIOLOGY OF INFLAMMATION THE ROLE OF CHEMICAL MEDIATORS IN THE INFLAMMATORY RESPONSE SHARED PHARMACOLOGY OF NONSTEROIDAL ANTIINFLAMMATORY DRUGS Chemistry Mechanism…
Table 6-4 Integration of Population Pharmacodynamic (PD) and Pharmacokinetic (PK) Data and Its Role in the Design of Dosing Regimens 6 Principles of Antimicrobial Therapy∗ Dawn Merton Boothe Chapter Outline…
Chapter 20 Drugs Affecting the Respiratory System Dawn Merton Boothe Chapter Outline NORMAL RESPIRATORY PHYSIOLOGY Airway Caliber Changes Respiratory Defense Mechanisms SURFACTANT PATHOGENESIS OF INFLAMMATORY RESPIRATORY DISEASES INFLAMMATORY MEDIATORS IN…
Table 27-2 Indications for Anticonvulsants in Humans Based on Seizural Activity Chapter 27 Anticonvulsants and Other Neurologic Therapies in Small Animals Dawn Merton Boothe Chapter Outline PHYSIOLOGY AND SEIZURE PATHOPHYSIOLOGY…
Chapter 16 Fluids, Electrolytes, and Acid–Base Therapy Reid P. Groman, Michael D. Willard Chapter Outline PHYSIOLOGY Water Sodium Potassium Acid–Base Balance DISEASE-INDUCED CHANGES Sodium Chloride Potassium Miscellaneous Minerals Acid–Base Status…
Table 30-2 Comparison of Glucocorticoid Free Bases Chapter 30 Glucocorticoids and Mineralocorticoids Dawn Merton Boothe, Katrina Mealey Chapter Outline PHYSIOLOGY: CONTROL OF ENDOGENOUS GLUCOCORTICOID SECRETION MECHANISM OF ACTION Mineralocorticoid and…
Chapter 15 Drugs Acting on Blood or Blood-Forming Organs Dawn Merton Boothe Chapter Outline DRUGS STIMULATING MEDULLARY POEISIS Bone Marrow Regulation Red Blood Cell Formation Drugs Affecting Red Blood Cell…
Chapter 21 Drug Therapy for Endocrinopathies Ellen N. Behrend, Tanya Civco, Dawn Merton Boothe∗ Chapter Outline DISEASES OF THE THYROID GLAND Synthesis of Thyroid Hormones Hypothyroidism Hyperthyroidism DISEASES OF THE…
Chapter 31 Immunomodulators or Biological Response Modifiers Introduction and Miscellaneous Agents∗ Dawn Merton Boothe Chapter Outline THE IMMUNE RESPONSE Immune Defenses Effectors Cellular Components Soluble Components Mucosal Immunity Antimicrobial and…
