The Role of the Dorsal Striatum in Instrumental Conditioning
7. Neuringer A, Deiss C, Olson G (2000) Reinforced variability and operant learning. J Exp Psychol Anim Behav Process 26: 98–111PubMedCrossRef 8. Yu C, Gupta J, Yin HH (2010) The…
Optical Approaches to Studying the Basal Ganglia
Fig. 1. Diagram of an optical workstation utilizing Prairie View (Prairie Technologies, Inc.) and Win Fluor (University of Strathclyde) software. The movement and gain of the imaging laser is controlled…
Quantification of Brain Function and Neurotransmission System In Vivo by Positron Emission Tomography: A Review of Technical Aspects and Practical Considerations in Preclinical Research
Fig. 1. Radiometabolites of [11C]-WAY-100635 after labelling in the 2-methoxy position or in the carbonyl of the amide group. In addition, the pharmacokinetics of the radiotracer and the biological process…
Genetic Models of Parkinson’s Disease
Fig. 1. The Tamoxifen inducible gene switch. (a) Gene inactivation in knockout mice or gene expression in standard transgenic mice is restricted to selected cell types but the timing of…
High-Throughput Mouse Phenotyping
Fig. 1. Test arena for open field test. At the beginning of the experiment, all animals are transported to the test room and left undisturbed for at least 30 min…
Neurological Evaluation of Movement Disorders in Mice
Fig. 1. Tests from the modified SHIRPA screen. Force touch assesses the reactivity of the mice to a touch on the back from above (a). The use of a beam…
Rotation in the 6-OHDA-Lesioned Rat
Fig. 1. Schematic illustration of the prototypical rotometer apparatus, (a) design based on the original Ungerstedt and Arbuthnott (3) description. (b) Design as currently used in the Brain Repair Group…
Behavioral Assessment in the African Green Monkey After MPTP Administration
Bipedal lookout Standing on legs with hands not touching the floor and gazing outside of cage. Legs may be standing on perch or other object, and hands may be resting…
Methodological Strategies to Evaluate Functional Effectors Related to Parkinson’s Disease Through Application of Caenorhabditis elegans Models
Database Web address Description WormBase http://www.wormbase.org/ Gene summary pages containing functional, structural, and phylogenetic information. Links to other databases (i.e., interactome, microarray databases, expression patterns, etc.), related to query genes…
Rodent Skilled Reaching for Modeling Pathological Conditions of the Human Motor System
Fig. 1. The single pellet reaching task and apparatus dimensions. An animal must walk from the back of the apparatus to the front, sniff to identify the presence of a…
