Surgical Considerations

Chapter 4 Surgical Considerations



4.1 Preoperative Preparation





Evaluation of the Patient


All animals that are surgical candidates should have a complete physical examination, including auscultation of the heart and lungs and an assessment of the surgical problem. For simple elective surgical procedures in young healthy animals, preoperative laboratory work is probably not necessary. Laboratory screening is of value for animals that undergo general anesthesia, those with a more complicated disorder, and those with significant potential hemodynamic complications associated with surgery (such as blood loss). Packed cell volume (PCV) and total protein (TP) are screening tests easily performed that may influence preanesthesia preparation and intraoperative response to blood loss. For cattle with complicated gastrointestinal disturbances, such as an abomasal volvulus, plasma electrolyte concentrations help determine appropriate replacement fluid therapy (see Chapter 5). A complete blood count would help identify animals affected with serious infectious processes and may influence preparation and the timing of surgery. If other systemic concerns about a farm animal, such as fatty liver syndrome in a cow, exist, specific tests such as a serum GGT can be run, or if finances permit, a large animal biochemical panel may be more appropriate.


Cattle that undergo elective surgical procedures under general anesthesia in lateral or dorsal recumbency should be fasted 24 to 48 hours before surgery to decrease the ruminal content and ruminal distension and risk of aspiration pneumonia. Furthermore, in ruminants subjected to general anesthesia, fasting is essential to improve venous return and ventilatory capacity (see Chapter 6).





Preparation of the Surgery Site


Once the decision is made for the surgical approach, dirt and manure should be removed. Hair should be clipped and a generous area left free of hair and debris. Some advocate shaving the actual site of the skin incision, but this may increase chances of infection if the skin is inadvertently nicked. As a rule of thumb, a 25-cm hairless margin around the surgical site is recommended.


In thick-skinned animals, an initial prep with a clean, stiff brush may be helpful. This should be followed by repeated scrubs with a disinfectant solution. Scrub solutions typically contain povidone (polyvinylpyrrolidone)-iodine, 4% chlorhexidine gluconate, or 2% chlorhexidine diacetate. Povidone iodine and chlorhexidine products have a broad antimicrobial spectrum, including most bacteria, some fungi, and many viruses. Scrub solutions can be rinsed with water, saline, or 7% isopropyl alcohol. For long procedures (longer than 90 minutes), povidone iodine with an alcohol rinse, or chlorhexidine with a water or saline rinse is recommended. To aseptically prepare a skin incision, the planned incision site should be cleaned and followed by a circular motion moving from the center to the periphery. This should be repeated at least three times. Depending on the skin gross contamination, more cleansing may be indicated; the gauze should be checked for cleanliness at the completion of the scrub. Some clinicians don a sterile glove and use sterile gauze for the final preparation. This incision site should be draped if at all possible. Impervious drapes can be placed over cloth or paper drapes to help keep the incision dry and free of infection. If the surgery becomes contaminated (for example, if an enterotomy is performed), the area should be isolated with drapes or towels, and the surgeons should reglove after the procedure.



Preparation of the Surgeon


In a hospital setting, clean, comfortable cotton or cotton-blend clothing with use restricted to the operating room is ideal and helps reduce the number of environmental contaminants. Some type of clean head covering that confines hair has also been shown to reduce the incidence of surgical infections. Caps, hoods, and bouffant-style coverings are some options. Facial coverings other than masks protect the wound from droplets of saliva and nasal exudates but are not effective bacterial filters. When properly fitted, face masks direct airflow away from the surgical wound, which—theoretically—should cut down on wound infection. Studies have not supported this finding, but masks are still recommended. Shoe covers are fairly impractical in most farm animal surgery, although waterproof shoes add to the surgeon’s comfort.


Surgical gowns are used for most lengthy procedures in a hospital environment. Lint-free gowns that are impervious to water and bacteria are most effective. Reusable gowns made of muslin or, more recently, of 270-count pima cotton, are somewhat resistant to water but not bacteria. Gowns treated with Quarpel, a flourochemical finish, combined with Pyridium or melamine hydrophobe, have a better barrier to water and bacteria and a pore size reduced to 10 μm. Gore-Tex fabric makes an even more durable bacteria-resistant gown.


Disposable gowns are made from olefin, which is regenerated cellulose, a petroleum by-product. Some gowns have extra layers of water repellent material in the sleeves to prevent constant dampness and subsequent capillary migration of skin flora, which lead to increased bacterial counts of surgical wounds. Advantages of disposable products are ease of handling and storage, and reduced bacterial contamination in the surgical environment compared to nondisposables. However, purchasing and disposing of disposable items is more expensive. Nondisposable gowns are more comfortable and less expensive but do need to be laundered and replaced on a regular basis.


Gloves should be worn for all surgical procedures. This helps avoid contamination from the residual flora on the surgeon’s hands. Gloves also protect the surgeon from any allergens or contact dermatitis. Most gloves are made of latex and come in a single-use package in a wide variety of sizes. Hypoallergenic vinyl gloves are available for those with latex sensitivity. Magnesium silicate powder is preapplied to most gloves to make them easier to don; therefore gloves should be rinsed before handling tissues. Gloves commonly develop holes and should be checked often for defects. Double gloving is used if extensive draping is required or contamination of the surgeon’s hands by sharp objects such as bony fragments and orthopedic implants is likely. Gloves can be applied with a closed or open gloving technique. Closed gloving techniques are preferred because the surgeon’s skin will not make contact with the outside of the gown cuff. An open gloving is recommended to replace a glove during a procedure. Otherwise, the cuff of the gown that has been exposed to skin and perspiration will be pulled over “clean” hands. Cuffs of the surgeon’s gown should be covered completely by gloves because the cuff material is not impervious to water penetration. Water often finds its way to the surgeon’s hands regardless of the material chosen; therefore plastic safety sleeves and double gloving are often helpful during procedures in which the surgeon’s hands and arms may be submerged. Although a gown is sterile when first applied, it should be remembered that only the front, above the waist, is considered sterile during the procedure.




Prevention of Peritonitis and Surgical Infection


The surgeon must always be aware of their potential to promote or prevent peritonitis or other infections of the surgical site development during surgery in the cow. It is often possible is to reduce the risk of infection before contamination ever occurs or to intervene between the time contaminants are first introduced into the abdomen and the development of infection.



PRECONTAMINATION


The optimum time to intervene in the development of a surgical infection is before a known or anticipated episode of contamination. Careful planning of the procedure will minimize the period of contamination, ensure adequate restraint, and minimize the use of potential adjuvants to reduce the risk of infection. Prophylactic antibiotics should be considered in planning any clean-contaminated or contaminated procedure and clean procedures in patients with identified risk factors. Common patient risk factors include preexisting nonbacterial inflammatory peritonitis, malnutrition, circulatory shock, and remote or systemic infection. In the latter case, elective procedures should be delayed until the preexisting infection can be treated and resolved. Similar steps should be considered when facilities, the animal’s behavior, or its condition increase the risk of contamination (see Section 4.7). Field conditions often involve less than optimal restraint facilities, fractious animals, limited control of external sources of contamination, and conditions that might predispose to unexpected recumbency during standing procedures (hypocalcemia, exhaustion, extreme peritoneal tension), all of which increase morbidity.


Antibiotics should be administered just far enough before surgery to maintain high serum levels throughout the period of contamination. Intravenous (IV) administration of a single dose 15 minutes before surgery or intramuscular (IM) administration 60 minutes before surgery achieves this goal for most antibiotics. Parenteral, subcutaneous, and intraperitoneal routes are not recommended for prophylaxis because the time to peak levels is longer and less predictable and because peak levels are lower in comparison to IV and IM routes of administration. If intraoperative sample collection for culture is planned, some prophylactic effect can still be obtained by intravenously administering an appropriate antibiotic immediately after sample collection.


Prophylactic antibiotics should be selected with as specific a spectrum as possible, based on probable contaminants. This can be based on knowledge of common contaminants from planned surgical sites (e.g., anaerobes for rumenotomy), culture results from potential sites of leakage or preexisting infection (e.g., culture results from an umbilical abscess), or by predicting other common infectious agents. The ability of antibiotics to penetrate fibrin or function in the presence of necrotic debris or altered pH should not be a major concern in antibiotic selection during the precontamination or contamination stages. Antibiotic options are provided in Appendix 1.



CONTAMINATION


Preventive measures are similar to those described for the precontamination stage, with a few additions. Prophylactic antibiotics can still be of some benefit, but they should be given intravenously to achieve high serum and tissue levels as soon as possible. If a source of contamination first develops intraoperatively, rapid steps to minimize the amount and distribution of contamination are indicated. For example, in gastrointestinal surgery, gross contamination should be localized whenever possible by exteriorizing the site of leakage or isolating it with laparotomy sponges; physically removing all accessible contaminants; and avoiding palpation unless absolutely necessary so that contaminants are not physically transported from the site of leakage to other sites in the abdomen. If the site can be adequately exteriorized to allow external drainage, localized lavage with a sterile isotonic fluid can help remove contaminants. However, generalized lavage is more likely to distribute high concentrations of organisms to potentially clean areas and is only recommended if the site cannot be exteriorized or dissemination has already occurred. Adding antibiotics to the lavage fluid may be indicated even if appropriate systemic antibiotics have been administered.


Other important considerations in the after care of the surgical farm animal are supplying adequate hydration (see Chapter 5), keeping neonates warm, and providing adequate nutrition and oral electrolytes.


Down cattle need excellent footing that keeps them from slipping. They need to be supported by having food and water where it can be reached. Good padding in a heavily bedded stall or on soft dirt is ideal. If cattle remain down for prolonged periods of time it may be necessary to try to get them up with well-padded hip lifts. Alternatively, cattle can be “floated” in a commercial tub (“Aqua cow”)* (Figure 4.1-3). This apparatus requires a fair amount of time, patience, and manpower. Regardless it has been successful in the right hands for recumbent cows that are amenable to therapy.





4.2 Perioperative Antimicrobials and Analgesics



The extra-label use of antimicrobials and analgesics is regulated under the Animal Medicinal Drug Use and Clarification Act of 1994 (AMDUCA) by the FDA Center for Veterinary Medicine. Penicillin and/or ceftiofur are the most commonly used perioperative antibiotics for cattle that undergo surgery without enterotomy. Each drug has its advantages and disadvantages: penicillin is more effective than ceftiofur against Arcanobacterium pyogenes and other bovine anaerobic pathogens. It should be used (alone or in combination with another compatible bacteriocidal drug) for surgery on anatomical locations that normally harbor anaerobic organisms (e.g., mouth, gastrointestinal tract, reproductive tract). Unfortunately, penicillin is not very effective against most gram-negative organisms, and the duration of withdrawal time for milk or meat is a disadvantage. At a dose of 27,000 IU/kg intramuscularly (~,12,000 IU/lb IM—a 50-mL dose for a 1250 pound animal), the suggested withdrawal time for milk is 5 days and for meat 16 days; whereas for the generally clinically ineffective label dose of 7000 IU/kg, the respective withdrawal times are 2 and 5 days. Ceftiofur sodium (Naxcel), when used at the label dosage, has the advantage of no withdrawal time for meat or milk; ceftiofur hydrochloride (Excenel) has only a 2-day meat withdrawal and no milk withdrawal time.


If an enterotomy is performed, broad-spectrum coverage may be required. A therapy that combines penicillin and ceftiofur (both at 2 to 3 times label dosage) often is used. In a hospital setting, intravenously (IV) administered penicillin salts (22,000 units/kg) are sometimes substituted for procaine penicillin to achieve higher tissue concentrations, but more frequent administration (q6h) is required. If a venous catheter is used for penicillin salt administration, the water-soluble form of ceftiofur can also be given by this route. Ceftiofur IV administration causes less tissue irritation and discomfort with high peak serum and tissue levels of the parent drug. Using the water soluble form of ceftiofur IV is acceptable because it achieves plasma and tissue levels of the parent drug; and its metabolite, desfuroylceftiofur, exceeds the MIC of many gram-negative organisms of veterinary importance, as does its IM or subcutaneous (SQ) use. The SQ administration has the advantage of preserving beef quality because less muscle irritation occurs in comparison to that associated with an IM injection. Another option is oxytetracycline use, a broadspectrum antibiotic that is moderately effective against gram-positive and gram-negative aerobic and anaerobic organisms. It is occasionally used at an extra-label frequency (6.6 to 11 mg/kg q12 h) to maintain higher tissue levels. Tetracycline is more lipid-soluble than either penicillin or ceftiofur; therefore higher tissue concentrations would be expected. Tetracycline disadvantages are its bacteriostatic activity and potential for causing renal failure when administered at high daily dosages and/or to dehydrated animals. At present, Liquamycin LA-200 is the only form of oxytetracycline with a label that allows use in lactating dairy cattle. Used at the label dose (6.6 to 11 mg/kg IV, SQ, or IM q 24 hr), the drug has a 28-day meat withdrawal and 4-day milk withdrawal.


All perioperative antibiotics should be administered only 1 to 2 hours before surgery so that the highest concentration of drugs is present when tissue is being incised and handled and when clots/fibrin are forming. If the surgery is uncomplicated (e.g., a routine laparotomy), many surgeons do not use antibiotics. If antibiotics are used, it is imprudent to use them for a shorter duration than the label recommendation. Most cattle antibiotics are labeled for 3 days minimum use. More complicated surgeries (e.g., enterotomy, internal fixation) require continuous treatment for at least 5 days. If infection is discovered at the time of or after surgery, treatment should be continued for longer periods. When bacterial infection is suspected before surgery, the decision to withhold preoperative antibiotics until a culture sample can be obtained should be based upon the location and predicted benefit of culturing the infected site. For most abdominal surgeries with preexisting infection (e.g., reticular or umbilical abscess), preoperative antibiotics are recommended because offending organisms are predictable, cultures are generally not taken, and some risk of spreading the infection at the time of surgery exists. Conversely, antibiotics are generally withheld for orthopedic surgery that involves presumably infected bone until a culture sample can be obtained. If an offending organism’s sensitivity is known from samples obtained before surgery, antimicrobial selection should be based upon the organism’s sensitivity, predicted drug(s) tissue levels, confidence in drug safety and cost, and FDA approval of extra-label use.


Florifenicol (nonlactating cows), enrofloxacin (beef cattle with respiratory disease only), and tetracyclines are occasionally used as perioperative antibiotics. Aminoglycosides combined with penicillin, ampicillin, or Ticarcillin/clavulanate are rarely used in calves—and then only with strict adherence to extra label use (Table 4.2-1). Antibiotics prohibited under all circumstances in food animals are given in Box 4.2-1.


TABLE 4.2-1 Combination Use of Antimicrobial Drugs in Farm Animal Surgerya,b



























NONANTAGONISTIC ANTAGONISTIC
Penicillin and aminoglycoside Penicillin and tetracycline
Ampicillin and aminoglycoside
Amoxicillin and aminoglycoside
Cephalosporin and aminoglycoside
Erythromycin and rifampin*
Trimethoprim and sulfonamide (TMP/S)*
TMP/S* and rifampin*
Sulfonamide and tetracycline
Lincomycin and spectinomycin
Enrofloxacin

* To be used in calves only.


Beef cattle for respiratory complications only.


a The American Association of Bovine Practitioners, in being cognizant of food safety issues and concerns, encourages its members to refrain from the intramuscular, subcutaneous, or intravenous extra-label use of the aminoglycoside class of antibiotics in bovines (Approved by the Board of Directors, December 1994).


b Until further scientific information becomes available, aminoglycoside antibiotics should not be used in cattle except as specifically approved by the FDA (Approved by the American Veterinary Medical Association House of Delegates, 1998).




Perioperative Analgesics


Perioperative analgesics are indicated in most surgical procedures to temper the initial inflammatory response and decrease swelling as well as to improve the appetite and general well-being of the patient. In cattle with routine, relatively nontraumatic surgery (e.g., omentopexy), perioperative analgesics commonly are not used simply because of cost and loss of product value as a result of milk withholding. This is particularly true if cattle are being treated perioperatively with ceftiofur, which has no withholding time. The most commonly used antiinflammatory drug is flunixin meglumine (1.1 mg/kg IV or IM). Flunixin is a cyclooxygenase inhibitor that provides excellent analgesia, including visceral analgesia, and is the only FDA-approved nonsteroidal antiinflammatory drug for cattle—albeit only for beef cattle and only IV. It may be indicated during the time of routine (one or more dosages) bovine surgery and in the immediate postoperative period when withholding times for milk and meat are not a major issue (when used only preoperatively at label dose, it incurs 10 days of meat withholding and 3 days of milk withholding).


Phenylbutazone (PBZ) and aspirin are other anti-inflammatory analgesics that historically have been used in food animals. Given that detection of PBZ at any level in food animals is considered illegal (milk and meat withdrawal are recommended at 10 and 45 days, respectively) and given the potential adverse reactions in human consumers, the Food Animal Residue Avoidance Databank (FARAD) strongly discourages PBZ use in any food animal. FARAD further discourages aspirin use in food animals for the following reasons: 1) no FDA approval for use in food animals; 2) flunixin is an available alternative; and 3) it has questionable efficacy (administered orally, the drug reaches baseline serum concentrations in 12 to 24 hours).


Additional analgesics that may be used are lidocaine, alpha-agonists, and butorphanol. Lidocaine is mostly used either for epidural administration to provide analgesia to the pelvic area during and after perineal or rectal surgery or as intravenous anesthesia (with a tourniquet) during surgery on a distal limb (15 to 30 ml lidocaine). Lidocaine is most commonly used as a local analgesic for cutting skin to prevent an animal from becoming fractious.


Xylazine epidurals (0.05 mg/kg) or Medetomidine 5 to 15 μg/kg may provide slightly better analgesic effects than lidocaine. Xylazine 0.03 mg/kg can be combined with lidocaine (0.2 mg/kg) for both fast-acting and long-lasting (4 to 5 hours) analgesia. Butorphanol may also be used intramuscularly or intravenously (0.1 mg/kg) for severe pain that cannot be adequately diminished with NSAID therapy. For information regarding the use of nonapproved antibiotics and analgesics, the reader is encouraged to consult Food Animal Residue Avoidance Data Bank at www.farad.org.




4.3 Facilities and Restraining Devices




Introduction


When working with livestock, one faces inherent risks to the safety of the animal and handler. Livestock, by their sheer size, are a threat to human safety. Fearful or aggressive animals with horns are exponentially more dangerous and can inflict significant injury—or even death. Bulls are always dangerous and unpredictable and should never be trusted. Dairy bulls, because of their extensive human contact, lack a natural fear of humans and may be overtly aggressive. Beef bulls generally react out of fear toward humans. The protective, maternal instinct of a cow with a calf makes them significantly more dangerous then a single cow. Because beef cows usually are not intensively handled, they are more dangerous than dairy cows. It has been suggested that the position of the hair whorl between a cow’s eyes correlates with the degree of agitation the cow demonstrates under restraint. Animals with whorls located high on the forehead, above the level of the eyes, were found to be more aggressive under restraint (high whorls, hot-headed) (Grandin, 1995).


Although small ruminants (sheep, goats, and calves) can inflict injury to their handlers, they are more likely to injure themselves when struggling against restraining devices or overly aggressive handlers. Sheep and goats have a strong herd instinct and become stressed when separated from herd mates. Stress adversely effects wound healing as well as general health, growth, and production. In pigs, stress has been associated with sudden death.



Animal Behavior


Consideration of the animals’ natural instincts will enable a handler to humanely and safely move and restrain livestock. Livestock are prey animals whose primary defense mechanism is sight and flight. They have evolved wide-set eyes that afford them extensive peripheral vision in surveillance of predators. With an angle of vision approaching 300 degrees, their only blind spot is directly behind them. To avoid startling an animal when approaching it, the handler should remain within its line of sight. Startling an animal could elicit struggling, provoke the animal to kick, or incite a stampede.


Panoramic vision provides prey animals a wide angle of vision but sacrifices depth perception. This is why cattle commonly balk at shadows, are reluctant to step across different colored floors, and closely inspect objects in their paths. Handlers should be patient. They should allow the animal to assess the danger of a situation or novel object before forcing it to enter a foreign environment or head gate.


Animals naturally maintain a safe distance between themselves and potential predators. This distance is the flight zone. If the flight zone is invaded, the animal will move away from the invader to reestablish an adequate safe distance. In relation to people, this distance is influenced by the amount of contact the animal has had with humans. Dairy cattle, which are handled daily, may have practically no flight zone and can be readily approached. Alternatively, beef cattle, which often have greater fear because of limited human contact, may require several meters of space. Sheep and goats commonly move as a herd, and the comfort level of the first animal establishes the flight zone for the herd.



Knots


Ropes are invaluable assets in animal restraint. However, a rope is only as good as the knot that is tied. There is a unique knot, with a particular advantage, for practically any situation imaginable. However, every animal handler should be proficient with the three knots covered in the following discussion.






Restraint of Cattle



MOVING CATTLE


One should take advantage of ruminants’ flight instinct when moving a single animal or a herd. The flight zone is entered slowly, steadily, and silently so the animal is not spooked. The rate at which the animal moves depends on how deeply and rapidly the flight zone is penetrated. If an animal gets too anxious or moves too quickly, the handler should back away and allow the animal to relax. Excited cattle are impossible to control and are more likely to be injured or injure a person. Cattle should be moved no faster than a walk.


The spatial relationship between the handler and the animal’s body dictates the direction the animal will move when approached. The animal’s shoulder is the point of balance. If approached caudal to the shoulder, the animal will move forward; if approached cranial to the shoulder, the animal will generally move backward.






HEAD RESTRAINT






KICKING


A major consideration for personal safety is the animal’s ability to kick. Cows are very deft kickers and are notorious for kicking to the side—“cow kicking.” They also kick forward surprisingly well, and can extend the leg as far cranial and dorsal as the shoulder. Cows are also very proficient at kicking straight backward. They may even “mule kick” with both hind feet at the same time. The safest place to stand when working at the hind end of a cow is immediately adjacent to the animal’s body, so that the cow pushes the handler away rather then delivering a harmful blow at the snap of the kick. When working cranial to the hind legs, the operator should stay out of reach of a forward kick by standing level with the animal’s shoulder at arm’s length.







SURGICAL POSITION




Casting


An animal may very effectively be maintained in lateral or dorsal recumbency by casting and rope restraint if no surgery table is available. The major disadvantage is that surgical procedures must be done at or near ground level, which may be inconvenient, uncomfortable, and exhausting, plus make it harder to maintain aseptic technique.


Casting is a technique used to force an animal to lie down (Figure 4.3-4). A loop of rope is placed around the animal’s neck with a bowline knot or a quick-release honda. Some people prefer to run the loop over the neck and between the front legs to prevent undue pressure on the trachea. Two half hitches are placed over the back so that the knots lie against the animal’s spine when tightened. The first half hitch is behind the shoulder, and the second is in the flank, cranial to the udder or caudal to the penis. With the head secured, the rope is pulled with steady pressure until the animal lies down. The rope is tied with a quick-release knot cranial to the second half hitch to maintain rope pressure and keep the animal recumbent. The front and hind legs are bound together with hobbles or ropes. The legs are extended and tied to sturdy supports to secure the animal. Alternatively, for a quick procedure, the hind legs can be tucked under the second half hitch. The animal can be balanced against a wall, between bales of straw, or supported manually if dorsal recumbency is required.




FOOT RESTRAINT




Front Feet


Raising the front feet is not as convenient as raising the back feet. The forelimb of an amenable cow can be raised manually. The handler’s shoulder is placed at the crux of the cow’s elbow. The dewclaws are grasped with one hand and the dorsum of the foot with the other. The handler presses his body into the cow’s shoulder to displace its weight to the contralateral foot and simultaneously lifts the dewclaws and hoof, thus forcing the leg to bend at the carpus. Once flexed, the carpus and lower leg can be rested on a straw bale while the foot work is done.


Alternatively, a rope method can be used to elevate the front feet. A rope is placed around the leg, dorsal to the fetlock, and passed over a ceiling beam hook. The foot is raised and bent at the carpus. A second rope can be used to pull the foot laterally away from the animal’s body to facilitate access to the foot. Both ropes should be secured with quick release knots for ease in untying.


A third option uses one rope tied above the fetlock, run over the back of the animal, and secured (Figure 4.3-6).


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Sep 3, 2016 | Posted by in SUGERY, ORTHOPEDICS & ANESTHESIA | Comments Off on Surgical Considerations

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