Lymphadenopathy

55 Lymphadenopathy



Astrid Nielssen



1. What is meant by the term lymphadenopathy?

The term lymphadenopathy is most commonly used to refer to enlargement of one or more lymph nodes. Lymph node enlargement typically arises secondary to either proliferation of cells arising from within the node or infiltration from cells arising outside of the node. Regional lymphadenopathy is the term used to refer to enlargement of one or more lymph nodes draining a focal anatomic area. Generalized lymphadenopathy is the term used to refer to enlargement of multiple lymph nodes draining multiple anatomic regions.


2. What is meant by the term reactive lymphadenopathy?

When normal lymphoid or mononuclear phagocytic cells within a lymph node proliferate in response to antigenic stimulation, the term reactive lymphadenopathy (or hyperplasia) is used to describe that condition.


3. What are some potential causes of reactive lymphadenopathy?

Any source of chronic antigenic stimulation can result in a reactive lymphadenopathy, including neoplastic disease, infections, and immune-mediated disease.


4. What is meant by the term lymphadenitis?

When inflammatory cells predominate within a lymph node the term lymphadenitis is used to describe that condition. The term suppurative lymphadenitis is used if neutrophils predominate; the term granulomatous lymphadenitis is used if macrophages predominate; and the term eosinophilic lymphadenitis is used if eosinophils predominate.


5. What are some potential causes of lymphadenitis in the dog?

Suppurative lymphadenitis can result from bacterial or fungal infections, enlarging tumors, infarction, or immune-mediated disease. Granulomatous lymphadenitis can result from certain bacterial and fungal infections, chronic immune-mediated diseases, foreign bodies, protozoal infection, or algal infection. Eosinophilic lymphadenitis can result from chronic allergic skin disease, parasitism, mast cell tumors, and phycomycosis.

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Jul 31, 2016 | Posted by in INTERNAL MEDICINE | Comments Off on Lymphadenopathy

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