Disorders of the Prostate

26 Disorders of the Prostate




The prostate encircles the neck of the urinary bladder such that the urethra runs directly through the center. There are two prostatic lobes, separated by fibrous tissue. Growth and function of the prostate are androgen dependent. Under the influence of testosterone and its metabolite, dihydrotestosterone (DHT), prostatic cells increase in number (hyperplasia) and size (hypertrophy). As long as a male dog is intact, progressive increase in prostate size will occur. Castration causes profound prostate atrophy.


The following are diagnostic tests used for identification of all types of prostatic disease:




Imaging of the prostate. Ultrasound is most commonly performed because it allows identification of abnormalities within the prostate tissue and can be used to guide aspiration or biopsy of the prostate (Figure 26-1). Plain radiographs do not allow accurate assessment of prostate size. Infusion of contrast medium, which appears very white on radiographs, into the urethra and urinary bladder may better allow definition of prostate disease.

Aspiration or biopsy of the prostate with submission of samples collected for cytology and culture. This usually is done with ultrasound guidance (Figure 26-2). Aspiration of the prostate does not require sedation; collection of a biopsy specimen does require sedation of the dog.





I. BENIGN PROSTATIC HYPERTROPHY/HYPERPLASIA







< div class='tao-gold-member'>

Stay updated, free articles. Join our Telegram channel

Jul 18, 2016 | Posted by in PHARMACOLOGY, TOXICOLOGY & THERAPEUTICS | Comments Off on Disorders of the Prostate

Full access? Get Clinical Tree

Get Clinical Tree app for offline access