Amino Acids and Immune Functions

Bauchart-Thevret C, Stoll B, Chacko S, Burrin DG (2009) Sulfur amino acid deficiency upregulates intestinal methionine cycle activity and suppresses epithelial growth in neonatal pigs. Am J Physiol Endocrinol Metab 296:E1239–E1250PubMedCrossRef

Bernard AC, Mistry SK, Morris SM Jr, O’Brien WE, Tsuei BJ, Maley ME, Shirley LA, Kearney PA, Boulanger BR, Ochoa JB (2001) Alterations in arginine metabolic enzymes in trauma. Shock 15:215–219PubMedCrossRef

Blecha F (2001) Immunology. In: Pond WG, Mersmann HJ (eds) Biology of the domestic pig. Cornell University Press, Ithaca, NY, pp 688–711

Brandtzaeg P, Pabst R (2004) Let’s go mucosal: communication on slippery ground. Trends Immunol 25:570–577PubMedCrossRef

Bronte V, Zanovello P (2005) Regulation of immune responses by L-arginine metabolism. Nat Rev Immunol 5:641–654PubMedCrossRef

Bruins MJ, Soeters PB, Deutz NE (2000) Endotoxemia affects organ protein metabolism differently during prolonged feeding in pigs. J Nutr 130:3003–3013PubMed

Bruins MJ, Soeters PB, Lamers WH, Deutz NE (2002) L-arginine supplementation in pigs decreases liver protein turnover and increases hindquarter protein turnover both during and after endotoxemia. Am J Clin Nutr 75:1031–1044PubMed

Burkey TE, Skjolaas KA, Minton JE (2009) BOARD-INVITED REVIEW: Porcine mucosal immunity of the gastrointestinal tract. J Anim Sci 87:1493–1501PubMedCrossRef

Burns CP (1975) Isoleucine metabolism by leukemic and normal human leukocytes in relation to cell maturity and type. Blood 45:643–651PubMed

Butler JE, Weber P, Sinkora M, Baker D, Schoenherr A, Mayer B, Francis D (2002) Antibody repertoire development in fetal and neonatal piglets. VIII. Colonization is required for newborn piglets to make serum antibodies to T-dependent and type 2 T-independent antigens. J Immunol 169(12):6822–6830PubMed

Calder PC (2006) Branched-chain amino acids and immunity. J Nutr 136:288S–293SPubMed

Calder PC, Yaqoob P (1999) Glutamine and the immune system. Amino Acids 17:227–241PubMedCrossRef

Cuaron JA, Chapple RP, Easter RA (1984) Effect of lysine and threonine supplementation of sorghum gestation diets on nitrogen balance and plasma constituents in first-litter gilts. J Anim Sci 58:631–637PubMed

Cunningham-Rundles S (2002) Evaluation of the effects of nutrients on immune function. In: Calder PC, Field CJ, Gill HS (eds) Nutrition and immune function. CABI Publishing, Wallingford, UK, pp 57–92

Curi TCP, Demelo MP, Deazevedo RB, Zorn TMT, Curi R (1997) Glutamine utilization by rat neutrophils: presence of phosphate-dependent glutaminase. Am J Physiol 42:Cl124–Cl129

Curi R, Newsholme P, Pithon-Curi TC, Pires-de-Melo M, Garcia C, Homem-de-Bittencourt PI Jr, Guimarães ARP (1999) Metabolic fate of glutamine in lymphocytes, macrophages and neutrophils. Braz J Med Biol 32:15–21

Deutz NE, Reijven PL, Athanasas G, Soeters PB (1992) Post-operative changes in hepatic, intestinal, splenic and muscle fluxes of amino acids and ammonia in pigs. Clin Sci 83:607–614PubMed

Dréau D, Lallès JP, Toullec R, Salmon H (1995) B and T lymphocytes are enhanced in the gut of piglets fed heat-treated soyabean proteins. Vet Immunol Immunopathol 47:69–79PubMedCrossRef

Ewaschuk JB, Murdoch GK, Johnson IR, Madsen KL, Field CJ (2011) Glutamine supplementation improves intestinal barrier function in a weaned piglet model of Escherichia coli infection. Br J Nutr 106:870–877PubMedCrossRef

Geudens N, Wuyts WA, Rega FR, Vanaudenaerde BM, Neyrinck AP, Verleden GM, Lerut TE, Van Raemdonck DEM (2008) N-acetyl cysteine attenuates the inflammatory response in warm ischemic pig lungs. J Surg Res 146(2):177–183PubMedCrossRef

Glassy MC, Fur long CE (1981) Neutral amino acid transport during the cell cycle of cultured human lymphocytes. J Cell Physiol 107:69–74PubMedCrossRef

Grimble RF (2001) Nutritional modulation of immune function. Proc Nutr Soc 60:389–397PubMedCrossRef

Grimble RF (2006) The effects of sulfur amino acid intake on immune function in humans. J Nutr 136:1660S–1665SPubMed

Han J, Liu YL, Fan W, Chao J, Hou YQ, Yin YL, Zhu HL, Meng GQ, Che ZQ (2009) Dietary L-arginine supplementation alleviates immunosuppression induced by cyclophosphamide in weaned pigs. Amino Acids 37:643–651PubMedCrossRef

Han GQ, Yu B, Chen DW, Xiang ZT, Chen Y, Chen H, Mao Q (2012) Effects of threonine on expression of immune-related genes of porcine intestinal epithelial cell infected with Pseudorabies virus in vitro. Chin J Anim Nutr 3:487–496

Hibbs JB (1991) Synthesis of nitric oxide from L-arginine: a recently discovered pathway induced by cytokines with antitumour and antimicrobial activity. Res Immunol 142:565–569PubMedCrossRef

Jahoor F, Wykes L, del Rosario MP, Frazer ME, Reeds PJ (1999) Chronic protein undernutrition and an acute inflammatory stimulus elicit different protein kinetic responses in plasma but not in muscle of piglets. J Nutr 129:693–699PubMed

Only gold members can continue reading. Log In or Register to continue

Stay updated, free articles. Join our Telegram channel

Apr 21, 2017 | Posted by in GENERAL | Comments Off on Amino Acids and Immune Functions

Full access? Get Clinical Tree

Get Clinical Tree app for offline access