INDICATIONS
- To control oral pain preoperatively, perioperatively, and postoperatively by focal and/or systemic routes using multimodal therapy
EQUIPMENT: MATERIALS
Injectable Opioids and Alpha-2 Agonists
- Buprenorphine
- Butorphanol
- Hydromorphone
- Morphine
- Oxymorphone
- Fentanyl
- Methadone
- Dexmedetomidine
- Xylazine
Local Anesthetics
- Bupivicaine, 0.5%
- 1-cc syringe
- 25–27-gauge, 1–3-in. hypodermic needles
- Dosage: cats and small dogs = 0.1 cc; medium dogs = 0.2 cc; large dogs = 0.3 cc
- Add buprenorphine (to double duration) at 3 µm/kg in same syringe1
Injectable Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
- Carprofen
- Meloxicam
Oral or Transmucosal Opioids
- Buprenorphine
- Methadone
- MS Contin (time-released formulation of morphine sulfate)
Oral NSAIDs
- Carprofen
- Meloxicam
- Other veterinary-labeled NSAIDs
MECHANISM OF LOCAL ANESTHETICS
- Inhibit sodium (Na) cations’ passage through ion-selective Na+ channels in nerve membranes by selectively binding these channels and thereby preventing nerve impulse transmission1
METHODS
Sites and Means for Control of Pain
- Local anesthesia agents and alpha-2 agonists will inhibit transduction at A-delta and C nocioceptors and transmission of pain to the spinal cord
- Anti-inflammatory drugs are known to act both peripherally at the site of inflammation and centrally to modulate spinal transmission
- Opioids can modulate pain centrally and locally
- N-Methyl-D-aspartic (NMDA) antagonists, such as ketamine,2 can greatly decrease central sensitization
PROCEDURE FOR REGIONAL ANESTHESIA
Anatomical Sites for Local Anesthetic Infusion3
- Maxilla: at the pterygopalatine branch of the maxillary nerve (an extension of the trigeminal nerve) as it courses through the pterygoid fossa ventral to the junction of the rostral/middle one-third of the zygomatic arch
- Access via the infraorbital foramen (Fig. 9-1)
- Premeasure hypodermic needle length from the infraorbital foramen to the junction of the rostral/middle one-third of the zygomatic arch (Fig. 9-2)
- Insert hypodermic needle slowly into the infraorbital foramen, extending caudally to the level of the pterygopalatine nerve branch
- Aspirate, rotate needle 90 degrees and aspirate, repeating the process to complete 360 degrees, infuse slightly, aspirate again; if no backflash of blood enters the syringe, infuse desired volume slowly
- Gently remove hypodermic needle and hold pressure on the injection site for 1 minute to avoid hematoma formation
- Regional anesthesia will affect the oral tissue from the point of injection to the midline and rostral, including the hard palate
- Access via the infraorbital foramen (Fig. 9-1)
- Mandible: at the entrance of the inferior mandibuloalveolar branch of the mandibular nerve (an extension of the trigeminal nerve) into the mandibular foramen
- Access the site by inserting the hypodermic needle medial to the ramus, caudal to the third molar tooth coursing caudally toward the angular process of the mandible; to establish a target, place a finger extraorally on the angular process and direct the needle toward and just short of your finger (Fig. 9-3)
- An alternate access is to imagine a line extending ventral from the lateral canthus of the eye; enter via the skin medial to the ventral cortex of the mandible coursing dorsally to a point approximately half the width of the body of the mandible4
- Aspirate and rotate the syringe as described above
- Infuse slowly and withdraw the needle; hold pressure as described above to prevent hematoma formation
- The mandibular tissues will be anesthetized from the point of injection site rostral to the midline and medial to but not affecting the tongue
- Access the site by inserting the hypodermic needle medial to the ramus, caudal to the third molar tooth coursing caudally toward the angular process of the mandible; to establish a target, place a finger extraorally on the angular process and direct the needle toward and just short of your finger (Fig. 9-3)