DEFINITION/OVERVIEW

Cutaneous and mucous membrane lesions of dogs and cats caused by papillomaviruses (PVs)
Warts or verrucae most common
Viral plaques, sometimes progressing to squamous cell carcinoma (SCC) or invasive carcinoma, recognized in dogs and cats
Bowenoid in situ carcinoma (BISC) most common PV in cats
Most verrucae of dogs are exophytic; raised or inverted papillomas not uncommon

ETIOLOGY/PATHOPHYSIOLOGY

SIGNALMENT/HISTORY

Dogs
- Two genetic virus types with at least six strains and six syndromes
  - Young dogs with footpad lesions
  - Discrete pigmented papules, plaques, nodules in young adult dogs
- Miniature schnauzer, pug: pigmented plaque
- Oral, ocular, and genital papillomas generally in young dogs
- Cutaneous papillomas at any age
Cats
- More common in older cats; associated with being immunocompromised (e.g., feline immunodeficiency virus [FIV])
- Cutaneous lesions

Dogs
- Cutaneous papilloma often pedunculated, consisting of fronds of epithelium, up to 1 cm in diameter and located anywhere
- Oral papillomas in young dogs involve lips, gums, tongue, palate, oropharynx, and esophagus; interfere with prehension and swallowing; trauma results in severe halitosis and ptyalism (Fig. 45-1)
- Lesions may be confined to genital or eyelid regions
- Inverted papillomas less common and often on ventral abdomen, up to 2 cm, and have a central pore
- Canine plaque most often seen in miniature schnauzer and pug; rarely transform to SCC; ventral abdomen and inner thigh regions often involved
Cats
- Exophytic papillomas exceedingly rare; more common are simple pigmented plaques, which may progress to BISC or to invasive carcinoma
- Cats often 10 years or older; may have other systemic disease causing immunosuppression (e.g., FIV)

Figure 45-1 Oral papilloma on the palate of a young dog.

(Image courtesy of Dr. Larry Baker)

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May 22, 2017 | Posted by admin in GENERAL | Comments Off