Wound Therapy
Topical Agents
Basic Information
Procedure
• Live yeast cell derivative (LYCD): Water-soluble yeast extract reported to stimulate angiogenesis, epithelialization and collagen formation. Associated with improved wound healing in dogs. In horses, it prolonged wound healing and resulted in excessive granulation tissue formation.
Reported to have both anti-thromboxane and anti-prostaglandin properties that favor vascular patency and prevent dermal ischemia.
AV extract gel with acemannan shown experimentally to encourage epithelialization and wound healing in open pad wounds in dogs at 7 days.
Therapeutic efficacy in horses not yet investigated and at least one study showed that AV delayed wound healing in this species.
Proposed advantages include wound debridement, antibacterial effect, and promotion of wound healing. Honey-treated wounds show little neutrophilic infiltration but marked proliferation of angioblasts and fibroblasts.
Bacteriostatic, reduces edema, attracts macrophages, debrides the wound, provides energy, and creates moist wound healing.
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