U

U



Urofollitropin



yoo-roe-fah’lih-troe-pin


Trade and Other Names: Metrodin, FSH, and Fertinex


Functional Classification: Hormone



Pharmacology and Mechanism of Action


Urofollitropin contains follicle-stimulating hormone (FSH) and stimulates ovulation. In people it is used in combination with human chorionic gonadotropin (hCG) to stimulate ovulation.



Indications and Clinical Uses


Although urofollitropin is used in people in combination with hCG to stimulate ovulation, the use in animals is not common.



Precautionary Information



Adverse Reactions and Side Effects


Side effects have not been reported in animals. In people, thromboembolism or severe ovarian hyperstimulation syndrome has been reported. In humans, ovarian enlargement and ovarian cysts have been reported.



Contraindications and Precautions


Do not use in pregnant animals.



Drug Interactions


No drug interactions are reported for animals.



Instructions for Use


Results of clinical studies in animals have not been reported. Use in animals is extrapolated from the experience in people. Use in humans is followed by administration of hCG.



Patient Monitoring and Laboratory Tests


Monitor estrogen and/or progesterone with treatment.



Formulations


Urofollitropin is available in 75 units per vial for injection.



Stability and Storage


Store in a tightly sealed container, protected from light, and at room temperature.

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Jul 18, 2016 | Posted by in PHARMACOLOGY, TOXICOLOGY & THERAPEUTICS | Comments Off on U

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