Polycystic Kidney Disease

Polycystic Kidney Disease



Basic Information image



Definition


Polycystic kidney disease is characterized by the development of multiple fluid-filled cysts within the kidneys, resulting in a reduction of functional renal mass.



Epidemiology



Species, Age, Sex


The age of presentation in reported cases is 9 to 15 years.



Genetics and Breed Predisposition


No breed predilection. Although it has not been shown to be inherited in horses, this disease is autosomal dominant (adult form) or autosomal recessive (juvenile form) in humans and autosomal dominant in long-haired and flat-faced cats.



Risk Factors


Breeding affected animals



Associated Conditions and Disorders


Chronic renal failure



Clinical Presentation



History, Chief Complaint




• Similar to other forms of chronic renal failure, weight loss, depression, lethargy, and anorexia


• Hematuria



Physical Exam Findings




• Weight loss


• Examination of the left kidney per rectum may reveal enlargement.



Etiology and Pathophysiology




• It is unknown if polycystic kidney disease in horses is an inherited condition as seen in other species.


• Cystic lesions most likely are congenital and increase in size over time, resulting in compression of surrounding renal parenchyma and eventually leading to chronic renal failure.

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Jul 24, 2016 | Posted by in SMALL ANIMAL | Comments Off on Polycystic Kidney Disease

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