Neoplasia, Esophageal

Neoplasia, Esophageal



Basic Information image



Definition


Neoplasia of the esophagus



Epidemiology



Species, Age, Sex


More likely in older horses



Clinical Presentation



History, Chief Complaint




• Clinical signs of recurrent esophageal obstruction.


• Weight loss.


• Inappetence or anorexia may be present in advanced cases.


• Recurrent colic (often associated with feeding) may be seen in some cases, especially if the patient has neoplastic involvement of the stomach as well as the esophagus.


• There may be a fetid odor around the mouth or nares.



Physical Exam Findings




• The findings on physical examination confirm the presenting signs, which include repeated bouts of esophageal dysphagia, hypersalivation, nasal discharge of saliva and food, retching, and bruxism.


• Persistent or intermittent pyrexia may occur with advanced neoplasia.



Etiology and Pathophysiology




• Squamous cell carcinoma is the most commonly reported neoplasm affecting the esophagus. In addition, extension of gastric squamous cell carcinoma into the distal esophagus may occur.


• In one reported case, squamous cell carcinoma developed within an esophageal diverticulum.


• Leiomyosarcoma has also been reported in association with gastric neoplasia.


• Exuberant granulation tissue in the esophagus without evidence of neoplasia has been reported in one horse.



Diagnosis image



Differential Diagnosis


Other causes of dysphagia (especially abnormalities of the pharyngeal and esophageal phases of deglutition), including pharyngeal paralysis, pharyngeal cysts, pharyngeal compression by strangles abscesses and guttural pouch empyema, subepiglottic cyst, fourth branchial arch defect, esophageal obstruction, megaesophagus, esophageal stricture, intramural esophageal cysts, esophageal rupture, and equine grass sickness.

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Jul 24, 2016 | Posted by in SMALL ANIMAL | Comments Off on Neoplasia, Esophageal

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