K

K


K 1. chemical symbol, potassium (L. kalium); symbol for kelvin. 2. equilibrium constant.


k symbol, kilo-.


κ kappa, small letter; tenth letter in the Greek alphabet.


K antigen see K antigen.


K cell killer cell.


K chain kappa chain.


K88 antigen a pilus antigen of Escherichia coli; provides adhesion of the bacteria to the epithelial lining of the intestine of piglets. Important in both neonatal and postweaning diarrhea. Called also F4.


K88 Escherichia coli scours the K88 antigen confers a potent pathogenicity on the serotypes of E. coli which carry it; the disease is an unusual form of neonatal scours in that some strains of E. coli lack the K88 antigen and that some families of pigs are not susceptible to the antigen.


K99 antigen pilus antigen of enterotoxigenic Escherichia coli of calves and piglets, responsible for adhesion of the bacterium to intestinal cells, which is essential for them to be pathogenic. Vaccines based on purified K99 antigen are used for the control of the disease. Called also F5 fimbriae.


kaalmelkbos Euphorbia mauritanica.


kaalsiekte [Af.] alopecia caused by Chrysocoma tenuifolia in lambs and kids; characterized by alopecia, pruritis, oculonasal discharge, alimentary tract obstruction by phytobezoar.


Kaeshi disease Ibaraki disease.


kaffir one of the types of grain sorghum.


kakiebos see Tagetes minuta.


kakosmia [kak-oz′meimage] cacosmia.


kala-azar [kah′lah-ah-zahr′] see leishmaniasis.


Kalanchoe genus of African and Madagascan plants in family Crassulaceae. Classified also as Bryophyllum spp. Includes K. daigremontiana, K. delagoensis (tubiflora), K. integra, K. lanceolata, K. luerbitiana, K. paniculata, K. pentheri, K. pinnata, K. rotundifolia, K. K. spathulata, K. thyrsiflora. Contain bufadienolide cardiac glycosides; some may cause krimpsiekte.


kale see Brassica oleracea.


marrowstem k. Brassica oleraceae var. acephala.


kalemia [kimagele′meimage] the presence of potassium in the blood. See also hyperkalemia.


Kalicephalus a genus of hookworm of the family Diaphanoce- phalidae, found in snakes.


kaliemia [ka″le-e′meimage] kalemia.


kaliopenia [ka″-o-pe′ne-d] hypokalemia.


kalium [L.] potassium (symbol K).


kaliuresis [ka″le-u-re′sis] excretion of potassium in the urine.


kaliuretic [ka″le-u-ret′ik] 1. pertaining to or promoting kaliuresis. 2. an agent that promotes kaliuresis.


kallidin [kalimagedin] kinin liberated by the action of kallikrein on a globulin of blood plasma. Kallidin I is the same as bradykinin; kal- lidin II is composed of bradykinin with a lysine added at the N-terminal.


kallikrein [kal′imagekre″in] any of a group of proteolytic enzymes present in various glands, lymph, urine, blood plasma, etc., or produced directly from mast cells or basophils, or indirectly from activated platelets. The major action of kallikreins is the liberation of kinins from α-2-globulins (kininogens), and they hence have vasodilator and whealing actions.


k.-kinin system an enzyme system which causes dilation of blood vessels and increases vascular permeability.


kallikreinogen [kal″i-kre-in′d-jdn] the inactive precursor of kallikrein which is normally present in blood.


Kallstroemia unidentified toxin in North American plants of this genus in the family Zygophyllaceae causes incoordination, weakness, convulsions. Includes K. hirsutissima (hairy caltrop), K. parviflora (warty caltrop).


Kalmia [kal′meimage] genus of North American trees in the family Ericaceae; contains the poisonous tetracyclic polyol, grayanotoxin (andromedotoxin); causes vomiting, incoordination, paralysis and hyperexcitability. Includes K. angustifolia (dwarf laurel), K. latifolia (mountain laurel), K. polifolia var. microphylla (hog laurel).


kamala [kah′mimagelimage] derived from the plant Mallotus philippinensis; previously used as an anticestodal agent, but now replaced by better and safer compounds. Used in herbal medicine as a purgative and externally to treat ringworm and scabies.


Kamer grip applied to the head of the foal or calf fetus for the purpose of rotating it. The palm is placed on the calf’s forehead with the thumb and the little finger each in an eye socket. It is then possible to pull, repulse and rotate the head.


kanamycin [kan″imagemi′sin] an aminoglycoside antibiotic active against many gram-negative and acid-fast bacteria; a high potential for nephrotoxicity. Similar to amikacin.


kangaroo a large jumping marsupial (Macropus spp.) in the family Macropodidae, native to Australia and New Guinea. Characterized by a very large tail, very powerful hindlegs and relatively underdeveloped forequarters. Large male kangaroos can stand 6 ft tall and may weigh up to 220 lb. The predominent species are the Eastern gray kangaroo (M. giganteus), the red kangaroo (M. rufus), Western gray kangaroo (M. fuliginosus), and the Antilopine kangaroo (M. antilopinus).


k. apples Solanum aviculare, S. laciniatum, S. simile, S. symonii, S. vescum, S. capsiciforme.


k. posture see kangaroo posture.


k. rat see kangaroo rat.


kangaroo gait a syndrome observed in lactating sheep in Australia, New Zealand and England consisting of a polyneuropathy which selectively affects the radial nerves. It is manifested by an inability to advance the front feet in a coordinated way, resulting in a bounding gait similar to that of a kangaroo. Affected ewes recover at the end of lactation.


Kansas horse plague see equine viral encephalomyelitis.


Kantrowitz forceps a curved clamp with serrations at the end designed for thoracic surgery.


kaolin [ka′o-lin] native hydrated aluminum silicate; used externally as an adsorbent and protective and internally as a gastrointestinal adsorbent and demulcent in mild diarrhea. The basis of the antiphlogistine poultice. Called also China clay.


Kapp-Beck clamp a ratchet-handled, scissor-type forcep used as a coronary sinus clamp. Has delicate, curved, claw-like blades.


Kapp-Beck-Thomson clamp used as a bronchus clamp; ratchet- handled, scissor-type forceps with heavy blades, set at an angle to the handles and with grooved faces on the blades.


kappa [kap′image] the tenth letter of the Greek alphabet, K or κ.


Karai virus a probable arbovirus isolated from Kenyan sheep which experience an unexplained mortality. Rhipicephalus evertsi ticks are suspected vectors.


karaka see Corynocarpus laevigatas.


karakin toxic nitrocompound in Corynocarpus laevigatus.


Karakul an originally Russian breed of wool and milk sheep that produces the curly coated fleece so desired by hat and garment makers in Asia. There are many sub-breeds producing a variety of colored wools, varying from traditional black, through gray, brown, to rose, and occasionally spotted. The desirable wool is obtained only from the pelts of full-term, newborn lambs. Survival for a few days or prolongation of pregnancy seriously reduces the financial worth of the pelt. Called also caracul, Astrakhan.


karanja see Pongamia glabra.


Karelian bear dog a Finnish dog breed used for hunting elk; named after a territory (Karelia) on the Russian-Finnish border. It is a large dog with a short, harsh black coat and white markings on the face, throat, chest, feet and tail tip. The tail is carried over the back and the ears are erect.



Kartagener′s syndrome [kahr-tag′imagenimager] a hereditary syndrome of humans consisting of dextrocardia, bronchiectasis and sinusitis. Cases of a similar disease are reported in dogs. The disease is primarily a defect in cilia motility. See primary ciliary dyskinesia.


Karwinskia humboldtiana [kahr-win′ske-image] North American plant in the family Rhamnaceae; contains an unidentified toxin; causes degeneration of skeletal muscles and axonal dystrophy in the cerebellum and spinal cord. The clinical picture includes hypersensitivity, tremor, ataxia, recumbency and absence of tendon reflexes. Called also coyotillo, buckthorn, tullidora.


kary(o)- word element. [Gr.] nucleus.


karyocyte a nucleated cell.


karyogenesis the formation of a cell nucleus.


karyogram [kar′e-o-gram″] a graphic representation of a karyotype.


karyokinesis [kar″e-o-kl-ne′sis] division of the nucleus, usually an early stage in the process of cell division, or mitosis


karyolymph the fluid portion of the nucleus of a cell, in which the other elements are dispersed.


karyolysis [kar″e-ol′imagesis] dissolution of the cell nucleus.


karyomorphism [kar″e-o-mor′fiz-imagem] the shape of a cell nucleus.


karyon [kar’e-on] the nucleus of a cell.


karyophage [kar’e-o-faj″] a protozoan that phagocytizes the nucleus of the cell it infects.


karyoplasm [kar’e-o-plaz″imagem] nucleoplasm.


karyopyknosis [kar″e-o-pik-no′sis] shrinkage of a cell nucleus, with condensation of the chromatin.


karyorrhexis [kar″e-o-rek′sis] rupture of the cell nucleus in which the chromatin disintegrates into formless granules that are extruded from the cell.


karyosome any aggregation of chromatin within a cell.


karyotheca [kar″e-o-the’kimage] the nuclear membrane.


karyotype [kar′e-o-tip] the chromosomal constitution of the cell nucleus; by extension, the photomicrograph of chromosomes arranged in numerical order.


karyotyping 1. preparation of a karyotype. 2. test to examine chromosomes in a sample of cells in terms of size, shape and number. It is used to identify problems that may result in reproductive disorders.


Kasen disease see equine allergic dermatitis. Also sometimes attributed to Onchocerca spp. infestation.


Kashmiri a goat; see Central Asiatic Pashmina.


Kaswan technique a method for repair of prolapse of the third eyelid gland (′cherry eye′) in which the gland is sutured to the orbital rim.


kat katal.


kata [kah′td] see peste des petits ruminants.


kat(a)- word element. [Gr.] down, against. See also words beginning cat(a)-.


katal (kat) [kafimagel] the SI unit of measurement to express activities of all catalysts, including enzymes, being that amount of a catalyst that catalyzes a reaction rate of 1 mole of substrate per second. katathermometer [kat”imagethdr-mom′imagetimager] a thermometer with a wet bulb and a dry bulb, for detecting cooling rates.


Katayama’s disease [kah-tah-yah′mah] schistosomiasis.


katipo see Latrodectus mactans.


kava [kah′vimage] Piper methysticum a plant of the western Pacific region and beverage prepared from it; sometimes marketed as a herbal supplement. Leaves and stems are ssociated with liver toxicity in dogs


kb kilobase; a thousand bases or nucleotides in a nucleic acid molecule. See also kbp.


kbp kilobase pair; for double-stranded nucleotides, a thousand nucleotide base pairs.


kcal kilocalorie.


KCS keratoconjunctivitis sicca.


44-kDa phosphoprotein see osteopontin.


Ke cycle within the Five element theory of traditional Chinese medicine, this is the restraining or controlling cycle which operates in the reverse direction to the Sheng cycle and together they maintain balance in the body.


kebbing see enzootic abortion of ewes.


ked [ked] see Melophagus ovinus.


keel 1. the ventrally directed large surface of the bird’s sternum, the site of attachment of the major muscles of flight. Called also carina. 2. the prominent area over the sternum in Dachshunds.


keeling the marking of ewes by the ram when they are mated by the marking on the ewe of paint or chalk from the sternum of the ram.


keep 1. to feed, e.g. long-keep steer. 2. pasturage.


Keeshond a medium-sized, short-coupled dog with very thick, medium length, ash gray haircoat that forms a characteristic ruff around the neck and is profuse on a tail that curls tightly over the back. The ears are small and erect and the face is fox-like. Black markings around the eyes (′spectacles′) give a fox-like expression. The breed is predisposed to atopy, epilepsy and heart defects. Called also Dutch barge dog.


keet a young guinea fowl.


Keith’s bundle a bundle of fibers in the wall of the right atrium between the openings of the venae cavae; see also sinoatrial node. Called also sinoatrial bundle, Keith’s node, Keith-Flack node.


Keith-Flack node [keth′ flak′] see Keith’s bundle.


KELA test kinetics-based, enzyme-linked immunosorbent assay.


Kjeldahl method method for determinin quantification of the amount of ammonia that undergoes sulfuric acid digestion followed by alkali distillation. Used for the calculation of crude protein in feedstuffs and other materials.


Keller spatula [kel′imager] an obstetrical spatula; a long-handled (3 ft) rod with a blunt spatulate tip, introduced into the uterus and manipulated from outside the cow or mare. Used to remove the skin of the fetus by blunt dissection.


Kelly-Murphy forceps conventional small hemostats with ratcheted handles and straight or curved blades with fine grooves running crossways inside the tip.


kelp see seaweed.


kelvin (K) [kel′vin] the SI unit of absolute temperature, equal to 1/273.16 of the absolute temperature of the triplepoint of water.


K. scale an absolute scale on which the unit of measurement corresponds to that of the Celsius (Centigrade) scale but the icepoint is at 273.16°C (273.16K).


kemps coarse hair fibers, found in a wool fleece; a cause for severe downgrading of value. The fibers are hard, brittle, opaque and medullated. They are shed after a short growing period and lie loose in the wool fibers; they will not take dye and will not spin together.


Kennel Club the principal body for maintaining stud books and registering purebred dogs in Great Britain.


kennel cough a highly contagious, acute respiratory disease of dogs, commonly consisting of laryngitis, tracheitis and bronchitis. It may be caused by any one or a combination of several viruses, bacteria and mycoplasmas, but predominantly canine parainfluenza virus (CPIV), canine adenovirus (CAV-1), and Bordetella bronchiseptica. Affected dogs usually have a harsh, dry (hacking) cough, and occasionally fever, serous nasal discharge and lymphadenopathy. Particularly in puppies, more severe illness sometimes occurs. Called also canine infectious tracheobronchitis, rhinotracheitis, canine cough.



kennelitis social maladjustment toward humans, seen in young dogs raised in a kennel rather than with humans.


Kent accessory bundle, Kent’s bundle [kent] the right-and left-sided myocardial conduction tissue bridge between the atria and the ventricles.


Kent Marsh [kent] see Romney Marsh.


Kenya Boran cattle an improved Kenyan version of Boran cattle.


Kenya SGPV Kenya sheep and goat poxvirus.


Kenya sheep/goat pox highly infectious disease of sheep and goats spread by contact; highly fatal in lambs; in adults a benign disease characterized by typical cutaneous pox lesions.


keraphyllocele [ker″image-fil′o-sēl] keratoma.


kerasin a cerebroside from brain tissue, yielding galactose, sphin- gosine and the 24C saturated fatty acid, lignoceric acid, on hydrolysis.


keratalgia [ker″d-tal′jimage] corneal pain.


keratan sulfate [ker′d-tan] a glycosaminoglycan which exists as either of two sulfated mucopolysaccharides (I and II). Keratan sulfate is an important component of the proteoglycan of cartilage, and occurs in the cornea and the nucleus pulposus.


keratectasia [ker″d-tek-ta′zhimage] corneal ectasia; protrusion of a thin, scarred cornea.


keratectomy excision of a portion of the cornea; kerectomy.


superficial k. removal of the corneal epithelium and anterior stroma on either a specified portion or the whole cornea.


keratic [kd-rat′ik] 1. pertaining to keratin. 2. pertaining to the cornea.


k. precipitates (KPs) multifocal aggregations of white blood cells and fibrin on the posterior (endothelial) surface of the cornea, especially ventrally. Pathognomonic for anterior uveitis.


keratin [ker′imagetin] a scleroprotein (fibrous structural protein) which is the principal constituent of epidermis, hair, nails, horny tissues, and the organic matrix of the enamel of the teeth. Its solution is sometimes used in coating pills when the latter are desired to pass through the stomach unchanged.


k. cyst see horn cyst.


k. pearl see keratin pearl.


k. tag see fibrovascular papilloma.


keratinase [ker′imagetimagenās] a proteolytic enzyme that hydrolyzes keratin.


keratinization [ker″imagetin″imageza’shimagen]the development of or conversion into keratin.


k. defects include hyperkeratosis, hypokeratosis, dyskeratosis. Diseases in which abnormal keratinization is an important feature include seborrhea, vitamin A responsive dermatosis, nasodigital hyperkeratosis, acne, parapsoriasis.


keratinocyte the cell of the epidermis that synthesizes keratin, known in its successive stages in the various layers of the skin as basal cell, prickle cell and granular cell.


k. transit time the time required for a keratinocyte to move from its origin in the actively dividing cells of the stratum basale to the surface of the epidermis where it is shed. Called also epidermal renewal time. In the normal dog, this is approximately 22 days.


Keratinomyces see Trichophyton.


keratinosome [kd-ratl-no-sōm″] small organelle in the intercellular space of the epidermis; it has a role in retaining water and in cell cohesion. Called also Odland’s body; cementasome.


keratinous [kimagerat′imagenimages] containing or of the nature of keratin.


keratitis [ker″imageti′tis] inflammation of the cornea. Keratitis may be deep (stromal) or superficial (epithelial); ulcerative or non-ulcerative, and due to trauma, bacterial, fungal, or viral infection, immune-mediated infiltration, etc.; or seen in association with a number of other ocular diseases such as blepharitis, entropion, ectropion, lagophthalmos, reduced tear quantity or quality, uve- itis, or glaucoma. Typical clinical signs include blepharospasm, serous to mucoid ocular discharge, corneal opacity and conjuncti- val or episcleral hyperemia.


chronic superficial k. as a descriptive term can be any long-term corneal inflammation centered on the epithelial surface or anterior stroma. By common usage has become synonymous with ′pannus′, an immune-mediated, progressive keratitis in dogs, particularly German shepherd dogs. Characterized by lymphoplasmacytic infiltration, vascularization, melanosis, edema and sometimes lipid/mineral deposition that usually commences at the temporal (lateral) quadrant and advances towards the center. The whole cornea may become involved. The cause is unknown, but exposure to ultraviolet light may be a factor. Called also CSK, pannus, Überreiter’s syndrome.



eosinophilic k. a superficial keratitis seen in horses and cats characterized by eosinophilic infiltration of the cornea typically resulting in a raised plaque. Usually begins at the temporal lim- bus. Can also affect the conjunctiva and/or eyelids. Scrapings of the affected tissue are diagnostic. The cause is unknown, but it has been associated with feline herpesvirus-1 in cats.


exposure k. vkeratitis resulting from ineffective or incomplete closure of the eyelids with subsequent drying of the precorneal tear film. Occurs due to dysfunction of cranial nerve V or VII, brachycephalic dogs with prominent globes and macropalpebral fissure (see lagophthalmos), and any animal during anesthesia.


herpetic k. inflammation of the cornea due to herpesvirus infections. Known in all domestic species for which a herpesvirus has been identified. Often seen in conjunction with conjunctivitis.


infectious k. corneal inflammation due to an infectious cause such as herpesvirus or Moraxella bovis.


interstitial k. inflammation of the corneal stroma, causing dense corneal opacification.


mycotic k. see keratomycosis.


neurogenic k. corneal inflammation as a result of dysfunction of cranial nerve V (see neurotrophic keratitis below) or VII (see neuroparalytic keratitis below).


neuroparalytic k. corneal inflammation resulting from impairment of the motor innervation (cranial nerve VII) of the eyelids protecting the cornea.


neurotrophic k. corneal inflammation resulting from impairment of the sensory (trigeminal) innervation of the cornea.


k. nigrum see corneal sequestrum.


pigmentary k. see corneal pigmentation and corneal melanosis.


k. sicca see keratoconjunctivitis sicca.


(superficial) pigmentary k. melanosis of the corneal epithelium and superficial stroma resulting from chronic keratitis from a variety of causes. Seen most commonly in brachycephalic dogs in which the contributing factors are exposure keratitis (due to lagophthalmos), distichiasis, lower medial entropion, nasal fold trichiasis and sometimes keratoconjunctivitis sicca.


superficial punctate k. ulcerative or non-ulcerative, bilateral corneal inflammation characterized by discrete superficial multifocal circular opacities. Cause unknown but altered tear film quality, dystrophy or immune-mediated disease have been implicated. Most common in the long-haired Dachshund.


ulcerative k. see corneal ulcer.


kerat(o)- word element. [Gr.] horny tissue, cornea.


keratoacanthoma [ker″imageto-ak″an-tho′mimage] see intracutaneous cornifying epithelioma.


keratocele [ker′imageto-sel″] hernial protrusion of Descemet’s membrane.


keratocentesis [ker″d-to-sen-te’sis] aqueocentesis.


keratoconjunctivitis [ker″d-to-kdn-junk″ti-vi′tis] inflammation of the cornea and conjunctiva.


chronic immune-mediated k. syndrome see chronic superficial keratitis.


infectious k. one caused by a primary corneoconjunctival pathogen, such as the herpesviruses, Moraxella bovis, and (in ruminants) Chlamydiae and Mycoplasma spp. See also infectious bovine keratoconjunctivitis (IBK).


proliferative k. one associated with a plaque-like mass, especially eosinophilic keratitis or nodular granulomatous episcleritis.


k. sicca comeoconjunctival inflammation due to reduced aqueous content of the precorneal tear film; marked by tenacious, adherent, stringy mucoid discharge, hyperemia of the conjunctiva, blepharospasm without epiphora, and a lack lust corneal appearance. With chronicity, thickening and melanosis of the corneal and conjunctival epithelium occur, in association with corneal neovascularization. Corneal ulceration accompanies acute onset. Called also ′dry eye′.


keratoconus [ker′imageto-ko′nimages] conical protrusion of the central part of the cornea.


keratocyte [ker′imageto-sit″] 1. a flattened cell lying between the collagenous corneal lamellae which constitute the corneal stroma. The keratocyte has branching processes that communicate with those of other keratocytes and is considered to be a resting fibroblast, which can be stimulated during wound healing to synthesize collagen. 2. a red blood cell with notches that results in projections that look like horns. Keratocytes occur when fibrin is being deposited within blood vessels as in disseminated intravascular coagulation.


keratoderma [ker″imageto-dur′mimage] hypertrophy of the horny layer of the skin.


keratodermia [ker″image-to-dur′me-image] keratoderma.


keratogenesis [ker″imageto-jen′imagesis] the production of keratin; a function of keratinocytes in the epidermis.


keratogenous [ker′imagetoj′imagenimages] giving rise to a growth of horny material.


keratoglobus [ker″imageto-glo′bimages] an anomaly in which the cornea is enlarged and globular in shape.


keratohelcosis [ker″imageto-himagel-ko’sis] ulceration of the cornea.


keratohemia [ker″imageto-he′me-image] deposition of blood in the cornea.


keratohyalin [ker″imageto-hi′imagelin] the substance in the granules in the stratum granulosum of the epidermis.


keratoid [ker′imagetoid] resembling horn or corneal tissue.


keratoiridoscope [ker″imagetoimagerid′imageskōp] a compound microscope for examining the eye.


keratoiritis [ker″imageto-i-ri′tis] inflammation of the cornea and iris. More commonly called keratouveitis because of the almost inevitable but often unobserved coincident inflammation of the ciliary body.


keratoleptynsis [ker″imageto-lep-tin’sis] removal of the anterior portion of the cornea and replacement with bulbar conjunctiva.


keratoleukoma [ker″imageto-bo-ko′mimage] a white opacity of the cornea.


keratolysis [ker″imagetoid-sis] loosening or separation of the horny layer of the epidermis.


keratolytic [ker″imageto-lit′ik] 1. pertaining to or promoting keratolysis. 2. an agent that promotes keratolysis.


keratoma [ker″imageto′mimage] keratosis.


digital k. see corn (1).


keratomalacia [ker″imageto-mimageb’shimage] softening or ′melting′ of the cornea associated with collagenase production by host corneal or white blood cells and microbial pathogens, especially gramnegative bacteria.


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Jul 18, 2016 | Posted by in PHARMACOLOGY, TOXICOLOGY & THERAPEUTICS | Comments Off on K

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