Interdisciplinary Evaluation of Toxicity in Ostreopsis Ovata: Algal Biotoxins

 

Samples received

Positive samples

% of positives

2008

250

50

20

2009

100

10

10

2010

400

2

0.5



The mice showed respiratory failure, posterior limb paralysis, and sometimes post-mortem eye opacity.

The chromatograms of the HPLC-MS tests are given in Fig. 19.1, and the results and comparisons between chemical and biotoxicological test results are given in Table 19.2.

A311736_1_En_19_Fig1_HTML.gif


Fig. 19.1
Examples of HPLC-MS test chromatograms: a Standard palytoxin (WAKO chemicals GmbH, Neuss, Germany); b Mussel samples collected offshore in La Spezia



Table 19.2
List of some samples tested for comparison with HPLC-MS and Mouse tests



























CRM code
Material
LC-MS
Mouse test

pPlTX
OVTX-a
Death times

(84100/6) G.SP.
Met extract mussels.
<LOD
<LOQ
2 h–3 h–3 h

(84100/7) G.SP.

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Sep 17, 2016 | Posted by in GENERAL | Comments Off on Interdisciplinary Evaluation of Toxicity in Ostreopsis Ovata: Algal Biotoxins

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