Increased Oxidative/Nitrosative Stress in Bitches with Several Tumors


Samples

SOD % inhibition

GPx U/ml Δ%

CAT μmoles/min/ml Δ%

Control skin (6)

10.6 ± 2.5

0.104 ± 0.04


491.1 ± 51.7


Histiocytoma (6)

17.3 ± 2.1

0.107 ± 0.03

2.9

418.5 ± 29.8

−14.7

Hemangiopericytoma(5)

*23.6 ± 2.7

*0.121 ± 0.04

16.3

*255.3 ± 26.3

−48.0

Control breast (5)

10.1 ± 2.1

0.097 ± 0.05


510.2 ± 47.9


Adenocarcinoma (8)

*43.4 ± 4.2

*0.341 ± 0.08

251.5

*129.8 ± 15.3

−74.5


*P < 0.01 compared with controls




Table 14.2
Nitrite and MDA levels in plasma and cytosol of various tissues (mean ± SD)

















































Samples

MDA (pmol/mg protein)

NO2 + NO3 (pmol/mg protein)

Plasma

Cytosol

Plasma

Cytosol

Control skin (6)

97.7 ± 9.9

109.7 ± 13.7

31.9 ± 3.6

44.9 ± 5.3

Histiocytoma (6)

106.4 ± 9.3

104.4 ± 12.6

26.5 ± 5.6

59 ± 6.6

Hemangiopericytoma (5)

*131.9 ± 14.8

*127.2 ±13.9

**44.8 ± 5.3

**105.2 ± 12.8

Control breast (5)

101.1 ± 11.5

107.8 ± 9.7

34.5 ± 3.9

40.7 ± 4.4

Adenocarcinoma (8)

**152.7 ± 18.4

** 148.4 ± 15.7

**56.4 ± 6.1

**86.5 ± 9.9

Sep 17, 2016 | Posted by in GENERAL | Comments Off on Increased Oxidative/Nitrosative Stress in Bitches with Several Tumors

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