Fibrinogen Basic Information Definition Fibrinogen is a soluble plasma protein produced by hepatocytes. Typical Normal Range (US units; SI units) Adults: 0.1 to 0.4 g/dL (1.0–4.0 g/L); varies slightly between reference laboratories. Values in healthy newborns (<24 hours) may be lower than adult reference intervals. Physiology Fibrinogen is important in coagulation, and it is a positive acute phase protein that increases with inflammation. Fibrinogen provides a substrate for fibrin formation and a matrix for migration of inflammatory-related cells. Causes of Abnormally High Levels • Dehydration • Inflammation: Increased fibrinogen production by the liver Next Diagnostic Step to Consider If Levels High Look for source of inflammation or dehydration: Perform minimum database (complete blood count, biochemistry panel, and urinalysis).< div class='tao-gold-member'> Only gold members can continue reading. Log In or Register a > to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: Aggressive Stallion Behavior Aflatoxin Toxicosis Biliary Atresia Black Widow Spider Toxicosis Stay updated, free articles. Join our Telegram channel Join Tags: Clinical Veterinary Advisor The Horse Jul 24, 2016 | Posted by admin in SMALL ANIMAL | Comments Off on Fibrinogen Full access? Get Clinical Tree
Fibrinogen Basic Information Definition Fibrinogen is a soluble plasma protein produced by hepatocytes. Typical Normal Range (US units; SI units) Adults: 0.1 to 0.4 g/dL (1.0–4.0 g/L); varies slightly between reference laboratories. Values in healthy newborns (<24 hours) may be lower than adult reference intervals. Physiology Fibrinogen is important in coagulation, and it is a positive acute phase protein that increases with inflammation. Fibrinogen provides a substrate for fibrin formation and a matrix for migration of inflammatory-related cells. Causes of Abnormally High Levels • Dehydration • Inflammation: Increased fibrinogen production by the liver Next Diagnostic Step to Consider If Levels High Look for source of inflammation or dehydration: Perform minimum database (complete blood count, biochemistry panel, and urinalysis).< div class='tao-gold-member'> Only gold members can continue reading. Log In or Register a > to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: Aggressive Stallion Behavior Aflatoxin Toxicosis Biliary Atresia Black Widow Spider Toxicosis Stay updated, free articles. Join our Telegram channel Join Tags: Clinical Veterinary Advisor The Horse Jul 24, 2016 | Posted by admin in SMALL ANIMAL | Comments Off on Fibrinogen Full access? Get Clinical Tree