Estrus, Prolonged
Basic Information
Clinical Presentation
History, Chief Complaint
Signs of estrus for >12 days (normal duration 5–7 days with a range of 2–12 days)
Etiology and Pathophysiology
• Seasonality: Prolonged estrous behavior during spring transition or winter anestrus
• Granulosa theca cell tumor (GTCT): Increased production of estrogens or lack of progesterone
• Gonadal dysgenesis: 63,XO; 65,XXX; 64,XY mares
• Hormone imbalance: Older mares may fail to ovulate and exhibit prolonged estrus; possibly due to insufficient or ineffective leutinizing hormone release
• Hemorrhagic anovulatory follicles (HAF): 14.3% remain as follicular structures with consequent signs of persistent estrus
Diagnosis
Initial Database
• Transrectal palpation and ultrasound: Serial examinations may be needed to evaluate the estrous cycle and its association with behavior.
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