Dermatitis, Atopic

Dermatitis, Atopic


image



Basic Information image



Definition


A hypersensitivity disorder in which the patient becomes sensitized to inhaled or percutaneously absorbed allergens such as dust, pollens, and molds, causing pruritus or urticaria.



Synonym(s)


Allergic inhalant dermatitis, allergies, atopy



Epidemiology



Species, Age, Sex


Age of onset is 1 to 6 years, although it can occur in older horses that have moved to different botanical zones.



Genetics and Breed Predisposition


Familial, Thoroughbreds, and Arabians may be predisposed.



Risk Factors


Genetic predisposition and sensitization to allergens at a young age



Geography and Seasonality


May be seasonal or nonseasonal and may be more common or severe in warmer areas with longer pollen seasons



Associated Conditions and Disorders


Insect hypersensitivity, eosinophilic granulomas, allergic airway disease, chronic obstructive pulmonary disease, or head shaking



Clinical Presentation



Disease Forms/Subtypes


Pruritus, urticaria, or pruritic urticaria



History, Chief Complaint


Seasonal or nonseasonal pruritus or urticaria



Physical Exam Findings


Alopecia and excoriations of the face, ears, neck, legs, or ventrum secondary bacterial folliculitis



Etiology and Pathophysiology


A type 1 hypersensitivity reaction in which an allergen is inhaled, ingested, or percutaneously absorbed, resulting in the production of allergen-specific IgE. When the IgE fixed on the surface of mast cells reacts with the offending allergen, mast cell degranulation occurs, causing release and production of various pruritogenic compounds such as histamine, leukotrienes, and prostaglandins.

< div class='tao-gold-member'>

Related posts:

  1. Fibrotic Myopathy
  2. Hepatitis, Bacterial
  3. Serum Bile Acid (SBA) Concentration
  4. Esophageal Stricture

Stay updated, free articles. Join our Telegram channel
Tags:
Jul 24, 2016 | Posted by in SMALL ANIMAL | Comments Off on Dermatitis, Atopic

Full access? Get Clinical Tree
Get Clinical Tree app for offline access