Branchial Cysts
Basic Information 
Epidemiology
Genetics and Breed Predisposition
This is a congenital abnormality, but no genetic or breed predisposition has been established.
Clinical Presentation
Etiology and Pathophysiology
• During the fourth week of embryonic life, the development of branchial (or pharyngeal) clefts results in five ridges known as the branchial (or pharyngeal) arches, which contribute to the formation of various structures of the head, neck, and thorax.
• The second arch grows caudally and, ultimately, covers the third and fourth arches. The buried clefts become ectoderm-lined cavities, which normally involute around week 7 of development.
• If a portion of the cleft fails to involute completely, the entrapped remnant forms an epithelium-lined cyst with or without a sinus tract to the overlying skin.
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