10. The most common adverse side effects of aminoglycoside antimicrobials are

11. Which statement regarding tetracyclines is true?

12. To what other drug class is a cephalosporin-class drug closely related?

13. Because of the manner in which they are excreted, sulfonamides are often effective against infections of

14. The use of fluoroquinolones as antiinfective agents should be done with great caution or not at all in

15. The antiinfective drug that should be avoided in all food-producing animals is

16. Penicillins are primarily excreted by the

17. Acepromazine must be used with caution or not at all in

18. The benzodiazepine derivative diazepam is often administered in combination with

19. If using a regular disposable-type syringe, which of the following drugs should not be preloaded and left for a time?

20. A 10-kg dog has inadvertently been administered a dose of xylazine hydrochloride intended for a 30-kg dog. The correct reversal agent for this overdose is

21. Griseofulvin acts on

22. What is not true of sulfonamides?

23. What antiinfective compounds, when given to juvenile animals, can impair cartilage development?

24. Potentiated penicillins

26. Xylazine

27. Propofol

28. Butorphanol

29. An iodophor

30. Heartgard contains ivermectin, which

31. The active drug in ProHeart is moxidectin, a member of the drug class

32. A risk to veterinary technicians who administer prostaglandins is

33. Loop diuretics such as furosemide

34. Pain receptors are called

35. If it is accidentally administered as an IV bolus, lidocaine may cause

36. Which of these opioids is an agonist/antagonist?

37. Acepromazine maleate causes

38. What is the ratio between the toxic dose and therapeutic dose of a drug used as a measure of the relative safety of the drug for a particular treatment?

39. Aspirin may be safely used in cats as an NSAID, but it should be noted that its half-life in this species approximates

40. Which statement is most accurate pertaining to insect growth regulators?

42. What is not a short-term effect of corticosteroid therapy?

43. A common side effect of antihistamine drugs such as diphenhydramine is

44. The H ₂ receptors are found in the

45. Thiobarbiturates should be administered with great care or not at all to

46. What drug is contraindicated in the treatment of glaucoma?

47. A chronotropic agent affects the

48. Puppies born via cesarean section that are not breathing well may benefit from __ drops administered sublingually.

49. Parenteral administration of phenylbutazone should be via __ only.

50. Intradermal injections are used primarily for

51. Most biotransformation of drugs occurs in the

52. The main reason that generic forms of drugs are less expensive than trademark name drugs is because generic brands

53. Repository forms of parenteral drugs

54. All of the following organs may facilitate the elimination of drugs except the

55. What liquid form of drug is most commonly administered intravenously?

57. The regulatory agency that oversees the development and approval of animal topical pesticides is the

58. A drug that has extreme potential for abuse and no approved medicinal purpose in the United States is classified as

59. A drug given by which of the following routes reaches its peak plasma concentration the fastest?

60. Which of these drugs is not an antifungal drug?

61. An example of an antibiotic that is considered to be a β-lactamase inhibitor is

62. In what class of antibiotic drugs are nephrotoxicity and ototoxicity potential side effects?

63. The best means of assuring that a particular antibiotic treatment will be successful is to

64. Dr. Blackman prescribed a particular antibiotic for a rabbit with a Pasteurella infection and asked you to educate the client regarding special instructions for administration of the drug. You told the client that she should wear gloves when handling this medication, because it has been associated with a rare adverse reaction in humans: aplastic anemia. Based on this information, the drug that you dispensed was most likely

65. The term anaphylaxis refers to

66. A very useful group of broad-spectrum drugs, whose popularity has more recently declined because of numerous potential side effects, including keratoconjunctivitis sicca, polyarthritis (especially in Doberman pinschers), hematuria, photosensitivity, and hypothyroidism, is the

67. Which of the following statements about tetracyclines is true?

69. Amoxicillin (Amoxi-Drop) was prescribed for Tallulah, a 4-year-old female Chihuahua, who was being discharged after a hospitalization. Dr. Segal asks you to give her owner discharge instructions. You advise the client of all of the following except

70. Antimicrobial drugs like enrofloxacin (Baytril), marbofloxacin (Zeniquin), and orbifloxacin (Orbax) all belong to which group of antibiotics?

71. Which of the following drugs is least likely to kill the normal flora in the gut of a rabbit, causing severe diarrhea?

72. Guaifenesin is an example of a(n)

73. Which of these drugs is available over the counter as an antitussive?

74. Dr. Charles is performing a C-section on Sadie, a 3-year-old Dalmatian. The smallest pup was not breathing spontaneously, so the doctor asked you give the following respiratory stimulant.

75. Butorphanol tartrate is an example of a drug that functions on more than one body system. It is both an

76. The type of drug that would be most helpful for a patient with a productive cough is

77. The anticoagulant diluted in saline or sterile water for injection to form a flush solution for preventing blood clots in intravenous catheters is

78. Sox, a 10-year-old M/C Siamese X, was brought to the emergency hospital, crying in pain and unable to walk. He was diagnosed with an arterial thromboembolism secondary to cardiomyopathy. The treatment for this condition is a(n)

79. The diuretic drug used most commonly in patients with congestive heart failure is

80. Epinephrine

82. Cosmo, an 11-year-old M/C pug, has recently been diagnosed with mitral insufficiency and was referred to a veterinary cardiologist. The specialist decided to initiate treatment with digoxin, a positive inotrope and negative chronotrope. This means that it

83. Scooter, a 13-year-old miniature schnauzer, has arrested under anesthesia for routine dentistry. You run to the crash cart and grab what you know to be the drug of choice for cardiac arrest, which is

84. A 3-month-old chow chow is presented to the pet emergency clinic because it has eaten a box of warfarin-based rat poison. Which of the following would be most useful to treat this toxicity?

85. Which of the following statements about drugs used for cancer chemotherapy is true?

86. Which of the following side effects is commonly seen with many cancer chemotherapeutic drugs?

87. Which of the following would be the least common side effect expected with common cancer chemotherapeutic drugs?

88. Common drugs of plant origin, such as digoxin and atropine, are ineffective in a cow when administered orally because of

89. Which of these tissues is not a normal site for drugs to accumulate to be released later, thereby prolonging the effect of the drug?

90. Chronic use of moderate-to-high doses of glucocorticoids may result in the development of

91. Glucocorticoids are often used in veterinary medicine for treatment of all of the following conditions except

92. Glucocorticoids have different durations of activity, a fact that plays an important role in their risk of side effects with long-term use. Which of the following glucocorticoids has the shortest duration of activity?

93. Which of the following statements about glucocorticoids is true?

95. Two relatively new NSAIDs used frequently in dogs for the relief of pain and inflammation, especially those associated with osteoarthritis, are

96. Flunixin meglumine (Banamine) is an NSAID most commonly used

97. The species that generally clears NSAIDs most slowly is

98. What NSAID is administered to cats with a dosing interval of 2 days or more?

99. The most common side effect of NSAIDs is

100. What precautions should you take when applying DMSO to an animal’s skin?

101. The surgeon has completed Buffy’s surgical procedure and asks you to discontinue the inhalant anesthesia. What is absolutely necessary to do when terminating anesthesia in a patient that has been receiving nitrous oxide?

102. All of the following drugs are controlled substances, and their use must be logged except

103. Malignant hyperthermia is a phenomenon associated primarily with the use of what inhalant anesthetic?

104. What drug is in the same class as thiopental?

105. An opioid analgesic often used in transdermal patches to control postsurgical pain is

106. Mrs. Stillman’s poodle Roxy has been diagnosed with idiopathic epilepsy. The doctor has decided to dispense what drug, which Mrs. Stillman can administer per rectum, in the event of a seizure at home?

107. A recent graduate veterinary technician is concerned that a sedated patient has a heart rate of 50 beats/min when the heart rate in a dog is normally 60 to 120 beats/min. You ask her which sedative the veterinarian used and were not at all surprised when she told you that the drug used was

109. You are asked to work in the surgical recovery area. Oreo, a cat, is recovering from an exploratory laparotomy. Oreo was given morphine, in addition to other drugs. You anticipate all of the following except that

110. What gas anesthesia demands the greatest degree of patient monitoring, because anesthetic depth changes occur most rapidly?

111. Norepinephrine, epinephrine, and dopa–mine are the primary neurotransmitters for the

112. Beuthanasia solution is back ordered at the distributor, so your employer asks you to order a different euthanasia solution. In researching the available drugs, you are reminded that the active ingredient in most euthanasia solutions is

113. You are working with an equine veterinarian on a breeding farm. You will be sedating a young stallion for an oral examination. You are well aware that the veterinarian will probably not be using what tranquilizer for the procedure?

114. The newly hired veterinary assistant is cleaning up after a procedure and returns an opened bottle of propofol (PropoFlo) to the refrigerator, stating that it can be used tomorrow on another patient. You explain to her that

115. You are out on an ambulatory call with Dr. Burrows to Milkman’s Dairy. You are asked to bring the xylazine from the truck to sedate the patient. You are well aware that when using this drug in the bovine, you must

116. You were assigned to work the front office at the hospital today. When you walk back to the treatment area, you notice a cat under anesthesia. The cat has eyes wide open and unblinking and limbs stiffly distended and is salivating profusely. Your highly educated guess is that this cat was anesthetized using which of the following drugs?

118. Acepromazine should be avoided in

119. The behavioral drug group that may be used to stimulate appetite in cats is

120. A progestin, often used in the past for the treatment of inappropriate elimination in cats, that has now fallen out of favor because of serious potential side effects, including mammary hyperplasia and adenocarcinoma, is

121. Which tricyclic antidepressant is now approved for used in dogs and cats to control separation anxiety?

122. A 12-year-old spayed female golden retriever is brought into your clinic with a history of waking up in her bed in a puddle of urine. A complete blood count (CBC), profile, and urinalysis reveal no sign of urinary tract disease. The doctor tells you to fill a prescription for phenylpropanolamine. The doctor is choosing this drug because

123. Erythropoietin (Epogen) is primarily used in the following feline patients:

124. Which of the following drugs is used to decrease gastric acid production by blocking histamine receptors in the stomach?

125. Amphojel and Basaljel are drugs in the general category of

126. Mr. Williams just adopted a mixed-breed puppy from the local animal shelter, and it was suggested that he bring it to a veterinarian to treat the worms noticed in its feces. Mr. Williams wanted to save some money and went to the local pet shop to buy a dewormer. The product that he purchased was most likely

127. A heartworm preventive that is also approved for the treatment of ear mites and sarcoptic mange is

128. If a drug package insert states that the drug is a coccidiostat, against what group of parasites will this drug be effective?

129. Which of the following drugs can cause severe tissue necrosis if given perivascularly?

131. By what route is insulin usually administered in cases of uncomplicated diabetes?

132. Insulin concentration is measured in

133. Oral hypoglycemic drugs, such as glipizide (Glucotrol), are used to treat

134. The primary function of insulin is to

135. Resuspension of NPH insulin is done by

136. Altrenogest, which is used for estrus synchronization in female animals, is a synthetic

137. Serious potential side effects of estrogen administration include

138. When diethylstilbestrol (DES), a synthetic estrogen, is used at higher doses, it can have the potentially dangerous side effect of

139. Kaolin and pectin (Kaopectate) and bismuth subsalicylate (Pepto-Bismol) are examples of

140. Psyllium and Metamucil are examples of

141. What is not a potential side effect of the phenothiazine antiemetics?

142. A stool softener often helpful in patients recovering from anal surgery is

143. The most widely used type of antiemetic drugs used to prevent motion sickness in dogs and cats are the

144. The emetic of choice in cats is

145. The emetic of choice in dogs is

147. A coating agent that forms an ulcer-adherent complex at the ulcer site is

148. Fleet (sodium phosphate) enemas are contraindicated in what species?